Neuroendocrinology: Pt. 1: The Normal Neuroendocrine System: 181 (Progress in Brain Research): Volume 181 - Hardcover

Hardcover

ISBN 10: 0444536175 ISBN 13: 9780444536174

Publisher: Elsevier Science, 2010

Synopsis

Neuroendocrinology is a discipline which originated about 50 years ago as a branch of Endocrinology and that is now strictly linked to neuroscience.

Volumes 181 and 182 of Progress in Brain Research provide a rapid view of the major points presently discussed at biological and clinical levels.

The chapters have been written by top scientists who are directly involved in basic or clinical research and who use the most sophisticated biotechnological techniques.

The volumes cover of the role of genetics in many endocrine-related events, like neuroendocrinological diseases and endocrine depenedent cancers (prostate, breast, etc,). Interesting information is also provided on possibile treatments of neurodegenerative brain diseases (e.g., Alzheimer and similar syndromes).

• The best researchers in the field provide their conclusions in the context of the latest experimental results
• Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
• Of great value for researchers and experts, but also for students as a background reference

About this title

About the Author

Donald W. Pfaff heads the Laboratory of Neurobiology and Behavior at The Rockefeller University. He received his scientific training at Harvard College and MIT. He is a Member of the U.S. National Academy of Sciences and a Fellow of the American Academy of Arts and Sciences. Pfaff's laboratory focuses on steroid hormones and brain function, genes influencing neuronal functions, and generalized CNS arousal. He is the author or coauthor of over 10 books and more than 900 research publications.

From the Back Cover

Neuroendocrinology is a discipline which originated 50 years ago when it was postulated that the hypothalamus might control the anterior pituitary gland through the synthesis of specific Releasing and Inhibiting Hormones. It soon became evident that the brain was responsible for the biosynthesis of many neuropeptides which acted as neurotransmitters, operating in strict cooperation with acetylcholine, the catecholamines and serotonin.

It was discovered that many recognized neuropeptides are directly produced in several peripheral tumors, facilitating their exact localization, suggesting the appropriate therapies and dictating their prognosis. Synthetic neuropeptides together with antiestrogens and antiandrogens are now considered crucial for the treatment of hormone-dependent cancers such as breast and prostate malignancies. Recent work has revealed that neuropeptides and steroid hormones may play a role in the treatment of the most common neurodegenerative diseases of the brain, such as Alzheimer’s.

Volumes 181 and 182 Research provide a comprehensive picture of the current field of neuroendocrinology, taking into account its two articulations: basic sciences (volume 181) and clinical applications (volume 182).

Edition details

• Publisher: Elsevier Science
• Publication date: 2010
• Language: English
• ISBN 10: 0444536175
• ISBN 13: 9780444536174
• Binding: Hardcover
• Number of pages: 312
• Editor: Martini Luciano, Chrousos George, Labrie MD PhD Fernand, Pacak Karel, Pfaff Donald W.