Gene and Cell Therapies: Principles of Pharmaceutical Development - Softcover

Van Der Walle

Softcover

ISBN 10: 0443457913 ISBN 13: 9780443457913

Publisher: Academic Press, 2026

Synopsis

Gene and Cell Therapies: Principles of Pharmaceutical Development explores increasing interest in gene and cell therapies following powerful demonstrations of their capability to treat rare genetic disorders, advanced cancers, and regenerate or repair tissues. Sections cover the design of viral vectors, oncolytic viruses, ribonucleic acid cancer vaccines, and autologous and allogeneic cell therapies, along with impacts on their pharmaceutical development. Advances in molecular and cell biology that have led to efficacious and safe gene and cell therapies are also covered, including their relationship to the process and analytical developments that ensure quality.

Gene and Cell Therapies: Principles of Pharmaceutical Development scope and style, along with included case studies, learning points, and lecture slides will allow non-specialists to develop a foundational understanding, while new concepts urge further advancements. Although these new, advanced medicines are continually being improved upon, their complex manufacture remains a key obstacle to increasing patient access.

• Discusses the concepts behind marketed and future gene and cell therapies
• Details information from the molecular level to manufacturing strategies
• Includes timely and thought provoking material for the student and professional in academia and industry
• Provides learning points, case studies, and lecture slides to support instructor teaching and student learning experiences

About this title

About the Author

Dr Christopher van der Walle
Head of Formulation Sciences
Science, Research and Innovation group
The Medicines and Healthcare products Regulatory Agency
Blanche Lane, South Mimms, Potters Bar
Hertfordshire, EN6 3QG,
United Kingdom
E: christopher.vanderwalle@mhra.gov.uk
W: nibsc.org
W: gov.uk/mhra

From the Back Cover

Interest in gene and cell therapies has increased dramatically following powerful demonstrations of their capability to treat rare genetic disorders, advanced cancers, and regenerate or repair tissues. Although these new, advanced medicines are continually being improved upon, their complex manufacture remains a key obstacle to increasing patient access. Gene and Cell Therapies: Principles of Pharmaceutical Development provides insight to the key principles of emerging scientific and technical strategies to overcome these obstacles. How the design of viral vectors, oncolytic viruses, ribonucleic acid cancer vaccines, autologous and allogeneic cell therapies, impacts their pharmaceutical development is outlined. The advances in molecular and cell biology that have led to efficacious and safe gene and cell therapies are related to the process and analytical developments that ensure their quality. The scope and style, along with included case studies, learning points and lecture slides, will allow the non-specialist to develop a foundational understanding, while the contemporary concepts discussed will urge further advancement of these exciting medicines.

Edition details

• Publisher: Academic Press
• Publication date: 2026
• Language: English
• ISBN 10: 0443457913
• ISBN 13: 9780443457913
• Binding: Paperback
• Number of pages: 238