Advancements in Modeling-Based Therapeutics and Technology for Chronic Diseases - Softcover

Softcover

ISBN 10: 0443338779 ISBN 13: 9780443338779

Publisher: Academic Press, 2025

Synopsis

Advancements in Modeling-Based Therapeutics and Technology for Chronic Diseases delves into the crucial role of animal and cellular models in comprehending the intricate mechanisms of chronic diseases. The book emphasizes the importance of these models in predicting disease progression, testing new therapeutic approaches, and understanding how environmental and genetic factors interplay in the development of long-term health conditions. With a multidisciplinary approach, it bridges the gap between experimental research and clinical applications, offering insights into not only disease management but also the future of personalized medicine.

The book also sheds light on emerging technologies, including bioinformatics tools and in silico modeling, which further enhance our ability to tackle chronic diseases. It explores how these advancements are transforming research methodologies and providing novel solutions for diagnosis and treatment. Additionally, it highlights collaborative strategies between researchers, clinicians, and technologists, stressing the importance of integrated efforts in addressing global health challenges effectively.

• Delves into detailed case studies, methodologies, and emerging trends, providing an in-depth review of current modeling approaches
• Explores the integration of various technologies, offering a holistic view of how these technologies can be applied synergistically
• Sheds light on how current technological innovations are integrated into therapeutic approaches for chronic disease management

About this title

About the Authors

Dr. Sachchida Nand Rai is a Biochemistry Research Associate at Banaras Hindu University’s Institute of Science. He obtained his MSc in Biochemistry from Purvanchal University, India, and his PhD in Biochemistry from Banaras Hindu University, India. Dr. Rai researches the anti-oxidative and anti-neuroinflammatory properties of phytochemicals for the treatment of neurodegenerative diseases. He is a lifetime member of the Indian Academy of Neuroscience.

Santosh Kumar Singh is a Senior Scientist at the Centre of Experimental Medicine & Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Dr. Veer Singh is currently working as Young Scientist (Department of Health Research) at the Department of Biochemistry, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Patna, India. He received his PhD from the Indian Institute of Technology (Banaras Hindu University), Varanasi. He has more than 45 publications with Internationally reputed publishers. He published two Indian patents. His area of work involves Environmental contamination and human health. He is also reviewer and guest editor of reputed publishers.

From the Back Cover

Advancements in Modeling-Based Therapeutics and Technology for Chronic Diseases explores the fundamental role played by animal and cellular models in unravelling the complexities of chronic diseases and underlying treatments. These models serve as crucial tools for scrutinizing the complicated molecular and cellular mechanisms underlying such diseases, conducting preclinical evaluations of pharmaceutical compounds, and probing into the genetic components contributing to disease pathogenesis and are the foundation of innovative therapeutic approaches for optimizing patient care in the treatment of chronic diseases. The book explores critical chronic diseases, providing insights into their complexities, causes, and potential therapeutic approaches. Content is organized into three sections. The first section begins with an introductory exploration of the intricate interplay of factors contributing to chronic illness burden then goes on to compare animal models, precision medicine and personalized drug design approaches, and advancements in biomarker discovery and validation used in targeted therapies. Further, this section intricately examines cellular and immunotherapy modelling as well as the role of transnational models for the management of chronic diseases. Various technological innovations in chronic diseases management are reviewed in the second section, including gene editing techniques in chronic disease treatment, image technologies for modelling and monitoring, computational tools and methods, as well as integrated systems biology approaches in chronic disease research. The book’s final section is devoted to discussing ethical and regulatory considerations, dilemmas and obstacles, with special focus on addressing data privacy concerns. In summary, this valuable resource offers a combination of current advances, practical insights, and treatment strategies, enabling scientists and researchers working in the field of modeling-based therapeutics for chronic diseases to stay abreast of novel developments and drive future direction in healthcare.

Edition details

• Publisher: Academic Press
• Publication date: 2025
• Language: English
• ISBN 10: 0443338779
• ISBN 13: 9780443338779
• Binding: Paperback
• Number of pages: 512
• Editor: Rai