ATP: From Neurotransmission to Cancer Therapy (Molecular Mediators in Health and Disease: How Cells Communicate) - Softcover

Softcover

ISBN 10: 0443302502 ISBN 13: 9780443302503

Publisher: Academic Press, 2026

Synopsis

ATP: From Neurotransmission to Cancer Therapy delivers a comprehensive discussion of extracellular ATP biology and its communication role in both homeostasis and pathologic states. It explores the function of ATP across the nervous, sensory, musculoskeletal, cutaneous cardiovascular, pulmonary, gastrointestinal, urinary, reproductive, exocrine, haematopoietic and immune systems. The book considers ATP in the context of various disease states, including cardiovascular, respiratory, psychiatric, inflammatory and neurodegenerative disorders, as well as pain and sensory disorders, infectious diseases, and cancer. ATP in humans is explored alongside other species, including rodents, fish, and plants. This is the latest volume in the “Molecular Mediators in Health and Disease” series. With contributions from specialists across pharmacology, physiology, biophysics, biochemistry, immunology, anatomy, molecular biology, therapeutics, and other critical fields, this volume provides a broad and detailed overview of ATP which will be helpful to researchers working in these areas and beyond.

• Considers extracellular ATP across various organs including the lung, heart, liver and kidneys
• Investigates ATP across a range of conditions such as age-related disorders, cardiovascular disease, respiratory disease and psychiatric disorders
• Explores the biochemistry and molecular biology of extracellular ATP signalling
• Looks at the history of ATP and its discovery in addition to future perspectives

About this title

About the Authors

Professor Ronald Sluyter received training in biochemistry and immunology. After completing his BAppSc (University of Technology, Sydney, Australia) and PhD (University of Sydney), he worked as a Research Fellow (2000-2003) and Senior Research Fellow (2003-2007) with the late Professor James Wiley at Nepean Hospital. Since 2008 he has held a tenured Aacdemic position at the University of Wollongong, being promoted to Professor in 2020. He is the author of over 137 original articles and book chapters. He has graduated over 16 graduate students.

Dr Jennie Cederholm received training in biomedical science, physiology and neuroscience. After completing her MSc (Linköping University, Sweden) and PhD (University of South Australia, Adelaide), she worked as a Research Officer (2007-2011) in what is today Neuroscience Research Australia (NeuRA). In 2011, she joined the laboratory of Professor Gary Housley as a Postdoctoral Fellow at UNSW Sydney. She holds a tenured Academic position since 2020 and was promoted to Senior Lecturer in 2021. She is the author of 26 refereed scientific publications. She has graduated 8 Honours students and is currently supervising 2 Honours students and a PhD student.

Associate Professor Leanne Stokes received training in physiology and pharmacology. After completing her MRes and PhD in immunology (University of Birmingham, UK), she worked as a postdoctoral researcher officer (2003-2006) at the University of Sheffield. In 2007, she joined the laboratory of the late Professor James Wiley as a Postdoctoral Fellow at University of Sydney before gaining independence through an NHMRC new investigator award (2009). In 2013 she moved to RMIT to take a position as a Vice-Chancellors Research Fellow (2013-2015). She holds a tenured Academic position since 2015 at the University of East Anglia (UEA) and was promoted to Associate Professor in 2020. She is the author of 54 refereed scientific publications. She has graduated 3 PhD students and is currently supervising an MSci student and a PhD student.

Prof. H Ulrich is Full Professor and Head of the Laboratory of Neuroscience at the Institute of Chemistry of the University of São Paulo, Brazil. He is a pioneer in the investigation of purinergic signaling in neuroinflammation, neurogenesis and neurodegeneration. He is a founding member of the Brazilian Purine Club (Brazilian Society of Purinergic Signaling), Vice-President (2010-2012) and President (2012-2018 and 2021-2024) of the society and has chaired many congresses of the Brazilian Purine Club. He is Associate Editor of several peer-reviewed journals, including Purinergic Signalling. He has published more than 260 peer-reviewed manuscripts (>10,000 citations, H index: 52), 31 book articles and 5 books and is inventor in various patents. He was recently awarded with the Brazil Fulbright Global Health Chair at Rutgers Medical School.

Associate Professor Srdjan Vlajkovic received training in medicine, immunology, and neuroscience. He worked at the Department of Physiology, University of Auckland as a Research Fellow and Senior Research Fellow and now holds a tenured academic position at the University of Auckland. He authored 88 original articles and book chapters and supervised 38 graduate students to completion. Dr Vlajkovic guest-edited several Special Issues in international journals and is currently the Academic Editor of the International Journal of Molecular Sciences and Frontiers journals.

Edition details

• Publisher: Academic Press
• Publication date: 2026
• Language: English
• ISBN 10: 0443302502
• ISBN 13: 9780443302503
• Binding: Paperback
• Number of pages: 1020
• Editor: Sluyter PhD Ronald, Cederholm PhD Jennie M.E., Stokes PhD Leanne, Ulrich PhD Henning, Vlajkovic PhD Srdjan, Tang PhD Yong