Pharmacology in Drug Discovery and Development: Understanding Drug Response - Softcover

Kenakin

Softcover

ISBN 10: 044314124X ISBN 13: 9780443141249

Publisher: Academic Press, 2024

Synopsis

Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization.

The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

• Fully updated, including two new chapters on the science of finding drug molecules
• Introduces the discipline to a scientist new to the area
• Demonstrates the value of pharmacology in the drug discovery process
• Presents a wide variety of techniques in simple terms
• Includes interactive exercises in the companion website

About this title

About the Author

Dr. Terry Kenakin is Professor of Pharmacology at the University of North Carolina School of Medicine. Prior to this, he spent 7 years in drug discovery at Burroughs-Wellcome. He then moved to GlaxoSmithKline for 25 years. Dr. Kenakin has written 11 books on Pharmacology, is the Editor in Chief of the Journal of Receptors and Signal Transduction, is on numerous Editorial Boards. He is the Editor-in-Chief of Comprehensive Pharmacology (Elsevier, 2022). He is the recipient of the 2008 Poulsson Medal for Pharmacology awarded by the Norwegian Society of Pharmacology for achievements in basic and clinical pharmacology and toxicology. He has also been awarded the 2011 Ariens Award from the Dutch Pharmacological Society and the 2014 Gaddum Memorial Award from the British Pharmacological Society, and the 2020 Goodman and Gilman Award in Receptor Pharmacology from ASPET.

From the Back Cover

Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization.

The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout. Dr. Kenakin successfully navigates a highly complex subject, making it accessible for students, professors, and new researchers working in pharmacology and drug discovery.

Edition details

• Publisher: Academic Press
• Publication date: 2024
• Language: English
• ISBN 10: 044314124X
• ISBN 13: 9780443141249
• Binding: Paperback
• Edition number: 3
• Number of pages: 444