Molecular Medicine: An Introductory Text - Softcover

Trent, R. J.

Softcover

ISBN 10: 0443053669 ISBN 13: 9780443053665

Publisher: Churchill Livingstone, 1997

Synopsis

The second edition of this popular book provides an overview of the impact which recombinant DNA (rDNA) technology is having on medical practice. Called molecular medicine, this rapidly expanding area has an increasing role to play in medicine, and this book addresses the importance of this challenging area. Molecular medicine is relevant to many medical disciplines, e.g. internal medicine, reproductive medicine, forensic medicine and laboratory practice. This new edition has been fully updated with the developments of the last few years. Key genes identified include BRCA1 (breast cancer) OB (obese) and those involved in DNA repair. In addition, the author covers the increase in gene therapy trials and the shifting of emphasis from genetic disorders to the cancers and HIV infection. For Departments of General/Internal Medicine: provides an overview of where rDNA technology fits into present day medicine and outlines what future applications could be. As such, it provides indications of overlap between what are traditional disciplines within General/Internal medicine, i.e. microbiology and internal medicine, therapeutics and internal medicine, etc. "Molecular Medicine" also introduces the reader to the complex ethical issues involved in this field. For Departments of Medical Genetics: "Molecular Medicine" puts developments in genetics in an overall framework so that a total picture is seen, putting what are sometimes seen as purely scientific findings into a clinical perspective. For Departments of Biochemistry/Molecular Biology: highlights the practical applications that Biochemistry and Molecular Biology has/will have to medical practice. For Departments of Pathology: "Molecular Medicine" highlights areas where rDNA techniques are important investigative tools for routine diagnostic tests or research activities, and outlines the interactions of this technology to other disciplines. For Departments of Medical Microbiology: developments in the fields of medical and forensic genetics often have meaningful repurcussions in the field of microbiology, and vice-versa. Students would have a better understanding of DNA technology if they were introduced to other aspects of genetic engineering. For Departments of Pharmacology: the potential for drug design using computer modelling is now a realistic therapeutic goal with the ablility to synthesize products through rDNA means. Any pharmacology department which ignores these major new developments, places itself and its students at adisadvantage. For Departments of Obstetrics & Gyneacology: the care of the fetus-in-utero or the neonate is an increasingly important aspect of O&G or a related fetal medicine unit. Obstetricians need to be aware of the rDNA implications (i.e. prenatal diagnosis and screening) to ensure the complete care of the pregnant woman. Acclaim for the first edition! Competitively priced...As a guide to the theory and applications of modern molecular techniques in medicine, this book is a superb introductory monograph - "The Journal of Clinical Pathology". This introductory and highly accessible text combines the minimum of technical details essential for understanding with a wealth of practical clinical examples...the text is admirably clear...excellent glossary...a valuable source for a multidisciplinary core curriculum in medical schools - "Trends in Genetics".

About this title

Review

"...represents an important contribution to the scientific audience as it separates the knowledge of molecular biology and defines it in molecular medicine terms. The book provides a different and unique perspective to the definition and implications of DNA in medicine. This is a high quality book with excellent art work that contributes significantly to the understanding of the text. As the field of molecular medicine expands, it is clear that textbooks such as this will continue to be needed."
- DOODY'S - 3 Stars(2005)

"The text, with its thorough multidisciplinary and interdisciplinary perspectives, provides an excellent resource for students and professionals working in microbiology, biochemisty, genetics, infectious diseases, molecular biology, and related fields."
- CLINICAL INFECTIOUS DISEASES (January 2005)

"The third edition is a compact primer of molecular medicine that should be very useful to the student or scientist...College and medical students, medical scientists and physicians, and scientists working in other fields who are interested in understanding the principles and methods of molecular medicine will find this a useful and compact introductory reference."
- Marshall Lichtman, University of Rochester Medical Center (2005)

Edition details

• Publisher: Churchill Livingstone
• Publication date: 1997
• Language: English
• ISBN 10: 0443053669
• ISBN 13: 9780443053665
• Binding: Paperback
• Edition number: 2
• Number of pages: 241