Excerpt from Endocrine Functions of the Pancreas
I am indebted to Dr. Gerald T. Evans for reading and criticizing the text.
I am grateful to Mrs. Marion Jacobson and her staff, to my mother, and particularly to my wife Elizabeth for their help in the preparation of the manuscript.
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Seller: Forgotten Books, London, United Kingdom
Paperback. Condition: New. Print on Demand. This book delves into the complex relationship between the pancreas and diabetes mellitus. It begins by tracing the discovery of the role of the pancreas in regulating blood sugar levels, from the initial observations in the late 19th century to the groundbreaking isolation of insulin in the 1920s. The author also explores the development of different animal models of diabetes, such as the alloxan-induced model, which have helped researchers better understand the disease. The book then examines the metabolic abnormalities that occur in diabetes, focusing on the impairment of carbohydrate metabolism and the resulting accumulation of ketone bodies. The author discusses the various theories that have been proposed to explain these metabolic changes, including the "overproduction theory," which suggests that diabetes is caused by an excessive production of glucose by the liver, and the "underutilization theory," which proposes that diabetes results from a decreased ability of tissues to utilize glucose. The author also explores the role of other endocrine glands, such as the pituitary and adrenal glands, in the regulation of carbohydrate metabolism and the development of diabetes. The book concludes by discussing the significance of the insights gained from the study of diabetes for our understanding of human metabolism and the development of new therapies for the disease. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item. Seller Inventory # 9780428139155_0
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