Items related to Animal Models in Cardiovascular Research
Synopsis
This fully revised and updated third edition reflects intensified interest in the field and provides information essential to researchers interested in using animal models for cardiovascular research, or any research requiring normal cardiovascular function.
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Review
`Every once in a while, one finds a text that is likely to be truly useful and a valuable addition to one's personal library. For those of us involved in cardiovascular research involving the use of whole animal models, such is this text.
Each chapter is prefaced with information of practical value for the researcher. The tables are subdivided by animal species and drug. ... This will be of tremendous value for anybody who is thinking about using a particular animal model for a research project and may save a good deal of time and effort.
For those of us who review grants and manuscripts for publication, this text should serve as a useful reference for normal values and for comparative studies so as to determine whether or not the work in question reflects a typical situation.
... the text is likely to be of considerable use and is highly recommended as an addition to the bookshelves of those of us involved in animal research. It will receive a prominent place in my library.'
Canadian Journal of Anaesthesia, 42:4 (1995)
From the Back Cover
Animal Models in Cardiovascular Research covers both historical and recent advances in our understanding of the cardiovascular system from studies conducted in animal models. The last decade has seen an explosion in the use of very specialized congenic and transgenic animal models that were not described in the previous two editions. The results of many of these studies provide a sometime bewildering array of redundant, overlapping and competing molecular pathways demanding further study. This third edition is designed to provide a better basis for understanding and using animal models in the current climate of background knowledge and information.
The first and second editions of Animal Models in Cardiovascular Research emphasized normal cardiovascular parameters and the cardiovascular effects of a wide variety of drugs commonly used for restraint, anesthesia and pain control in the various animal species. The third edition is focused on the avalanche of genetic, molecular and protein-based information generated from the use of both congenic and transgenic animal models. Updated and expanded chapters provide new information generated from classical, congenic and transgenic animal models used to study ischemic heart disease, cardiomyopathy, heart failure, hypertension and atherosclerotic disease.
Completely new chapters in this third edition describe the techniques, problems and pitfalls associated with the measurement of cardiac and vascular function and ventricular/arterial coupling dynamics in various animal models. There is a new chapter detailing problems and pitfalls associated with isolated heart preparations and another describing animal models for the study of neurohumeral and CNS control of the cardiovascular system.
"About this title" may belong to another edition of this title.
- PublisherSpringer
- Publication date2009
- ISBN 10 0387980822
- ISBN 13 9780387980829
- BindingPaperback
- LanguageEnglish
- Number of pages460
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