Synopsis
This book contains the papers that were presented at the "Crystallo- graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989. During the past few years, there has been a burst of activity in this area, especially related to drug design and protein engineering projects. The purpose of the symposium and this book is to provide an up-to- date review of the most recent experimental and theoretical approaches that are being used for molecular design. The book covers several re- cent examples of approaches for using crystallography in conjunction with forefront modeling methods for guiding the development of en- zyme inhibitors and of peptides and proteins with modified biological and physical properties. In addition, this book contains discussions of new approaches for combining crystallographic data and advanced computational techniques for aiding in the design of enzyme inhibitors and other compounds that bind to selected biological targets. This book is therefore of interest not only to molecular biologists and biochem- ists, but is stimulating reading for anyone involved in structural biol- ogy, pharmaceutical chemistry, enzymology, protein engineering, and biotechnology. The meeting was the third in a series of symposia initiated and spon- sored by the Department of Biochemistry, University of Alabama at Birmingham.
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Synopsis
This up-to-date review of forefront approaches used in structure-based drug design and protein engineering is intended for chemists, molecular biologists, pharmacologists, crystallographers, computer modelers, and graduate students interested in drug design and protein engineering. Leaders in protein crystallography, molecular dynamics, computer graphics, and molecular modeling report on their major contributions to this rapidly evolving field. Readers can expect to obtain an overall introduction to the major approaches that are now being pursued in structure-based drug design and protein engineering.
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Crystallographic and Modeling Methods in Molecular Design.
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Hardcover. Condition: Very Good. xvii 268p hardback with green laminated boards, colour plates, excellent fresh copy, minimal library marking, almost as new Language: English. Seller Inventory # 158085
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Crystallographic and Modeling Methods in Molecular Design
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Springer-Verlag, New York, NY, 1990
ISBN 10: 0387972102
ISBN 13: 9780387972107
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Hardcover. Condition: Near Fine. First Edition; First Printing. First Edition USA (1990) , unstated. First Printing indicated by a complete numerical sequence. Fine: flawless; the binding is square and secure; the text is clean. Free of any creased or dog-eared pages in the text. Free of ownership names, dates, addresses, notations, inscriptions, stamps, or labels. A handsome, like-new copy, structurally sound and tighly bound, showing no discernible imperfections. Bright and clean. Corners sharp. Appears unopened and unread. NOT a Remainder, Book-Club, or Ex-Library. 8vo. (9.5 x 6.3 x 0.75 inches) . Illustrated with 106 figures, graphs, tables, charts in black & white. Language: English. Weight: 21.1 ounces. Hardback: No DJ 'as issued'. ; Large 8vo 9" - 10" tall; xvii, 269 pages. Seller Inventory # 57994