Bioinformatics and the Cell: Modern Computational Approaches in Genomics, Proteomics and Transcriptomics

0 avg rating
( 0 ratings by Goodreads )
 
9780387713366: Bioinformatics and the Cell: Modern Computational Approaches in Genomics, Proteomics and Transcriptomics
View all copies of this ISBN edition:
 
 

The many books that have been published on bioinformatics tend toward either of two extremes: those that feature computational details with a great deal of mathematics, for computational scientists and mathematicians; and those that treat bioinformatics as a giant black box, for biologists. This is the first book using comprehensive numerical illustration of mathematical techniques and computational algorithms used in bioinformatics that converts molecular data into organized biological knowledge.

"synopsis" may belong to another edition of this title.

Review:

From the reviews:

"In this book the author makes an ‘effort to render both mathematical equations and biology to numbers’. ... he works out a lot of illustrative examples to make biologists understand the mathematics and computational scientists understand the biology of a wide range of problems in bioinformatics. ... The book is addressed to graduate students majoring in sciences and software engineering. Biologists with a sound knowledge of computer programming should be able to implement the presented algorithms in their own programs." (Wiebke Werft, Zentralblatt MATH, Vol. 1166, 2009)

From the Back Cover:

"Xuhua Xia’s Bioinformatics and the Cell is a welcome addition to the bourgeoning field of bioinformatics text books. Xia stakes out a too-often neglected middle ground in bioinformatics by presenting a work that emphasizes methods’ biological utility without eschewing algorithmic formalism. Readers will find a well-rounded presentation of bioinformatics techniques employed in genomics, transcriptomics and proteomics – unified throughout by the common theme of molecular evolution."

- I. King Jordan, School of Biology, Georgia Institute of Technology

"Bioinformatics and the Cell is a remarkable book because it integrates the more technical and mathematical aspects of bioinformatics with concrete examples of their application to current research problems in molecular and cellular biology. I believe that this broad, unified approach is made possible, in large part, by the very wide scope of Dr. Xia’s own research experience. The integration of genomics, proteomics and transcriptomics into a single volume makes this book required reading for students entering the new and emerging field of Systems Biology. This is truly a path breaking book."

- Donal Hickey, Concordia University, Montreal, Quebec, Canada

Bioinformatics and the Cell is the first book with comprehensive numerical illustration of mathematical techniques and computational algorithms used in bioinformatics to convert the rapidly increasing molecular data into organized biological knowledge, with a focus on interactions among DNA, RNA and proteins in the cell. A sample of the illustrated algorithms includes:

  • String matching algorithms with associated statistics
  • Sequence alignment with the affine function and profile alignment for multiple sequence alignment
  • Contig assembly algorithms
  • Perceptrons
  • Hidden Markov models
  • Gibbs sampler
  • Self-organizing map
  • Algorithms in molecular phylogenetics
  • EM algorithm for maximum likelihood calculation
  • Monte Carlo integration and Markov chain Monte Carlo algorithms for Bayesian inference
  • Mass deconvolution and computational methods for peptide mass fingerprinting

By rendering both mathematics and biology to numbers, this book should appeal not only to biologists, but also to mathematicians, biostatisticians, and computational scientists, especially those younger ones with an ambition to conquer the rough terrain of bioinformatics.

Dr. Xuhua Xia obtained his PhD in population biology at University of Western Ontario in 1990 and made his entry into molecular evolution and phylogenetics at University of Washington in 1993. He was recruited by University of Hong Kong in 1996 as an assistant professor, and served as a senior scientist and the founding head of the Bioinformatics Laboratory of HKU-Pasteur Research Centre. Dr. Xia joined University of Ottawa in 2002 where he is cross-appointed to both Biology Department and the School of Information Technology Engineering. He is an active member in the Center for Advanced Research in Environmental Genomics and the Ottawa Institute of Systems Biology. His web site is at http://dambe.bio.uottawa.ca.

"About this title" may belong to another edition of this title.

Other Popular Editions of the Same Title

9781441943910: Bioinformatics and the Cell: Modern Computational Approaches in Genomics, Proteomics and Transcriptomics

Featured Edition

ISBN 10:  1441943919 ISBN 13:  9781441943910
Publisher: Springer, 2010
Softcover

9788184897142: Bioinformatics and the Cell: Modern Computational Approaches in Genomics, Proteomics and Transcriptomics

Softcover

Top Search Results from the AbeBooks Marketplace

International Edition
International Edition

1.

Xia
ISBN 10: 0387713360 ISBN 13: 9780387713366
New Quantity Available: 2
International Edition
Seller:
firstbookstore
(New Delhi, India)

Book Description Condition: Brand New. Brand New Paperback International Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!. Seller Inventory # ABOCT-5178

More information about this seller | Contact this seller

Buy New
33.53
Convert currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, rates & speeds
International Edition
International Edition

2.

Xia
ISBN 10: 0387713360 ISBN 13: 9780387713366
New Softcover Quantity Available: 2
International Edition
Seller:
Romtrade Corp.
(STERLING HEIGHTS, MI, U.S.A.)

Book Description Condition: New. Brand New Paperback International Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery.This item may ship fro the US or other locations in India depending on your location and availability. Seller Inventory # AUOCT-5178

More information about this seller | Contact this seller

Buy New
35.59
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

3.

Xuhua Xia
Published by Springer
ISBN 10: 0387713360 ISBN 13: 9780387713366
New Quantity Available: 1
Seller:
Books Puddle
(New York, NY, U.S.A.)

Book Description Springer. Condition: New. pp. 368. Seller Inventory # 26267833

More information about this seller | Contact this seller

Buy New
132.51
Convert currency

Add to Basket

Shipping: 3.15
Within U.S.A.
Destination, rates & speeds

4.

Xia Xuhua
Published by Springer
ISBN 10: 0387713360 ISBN 13: 9780387713366
New Quantity Available: 1
Seller:
Majestic Books
(London, ,, United Kingdom)

Book Description Springer. Condition: New. pp. 368 131 Illus. Seller Inventory # 7580134

More information about this seller | Contact this seller

Buy New
149.02
Convert currency

Add to Basket

Shipping: 5.50
From United Kingdom to U.S.A.
Destination, rates & speeds

5.

Xuhua Xia
Published by Springer (2007)
ISBN 10: 0387713360 ISBN 13: 9780387713366
New Hardcover Quantity Available: 1
Seller:
Ergodebooks
(RICHMOND, TX, U.S.A.)

Book Description Springer, 2007. Hardcover. Condition: New. 2007. Seller Inventory # DADAX0387713360

More information about this seller | Contact this seller

Buy New
157.22
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

6.

Xia, Xuhua
Published by Springer
ISBN 10: 0387713360 ISBN 13: 9780387713366
New Hardcover Quantity Available: 1
Seller:
Cloud 9 Books
(Wellington, FL, U.S.A.)

Book Description Springer. Hardcover. Condition: New. 0387713360 New Condition. Seller Inventory # NEW33.3422769

More information about this seller | Contact this seller

Buy New
184.72
Convert currency

Add to Basket

Shipping: 3.94
Within U.S.A.
Destination, rates & speeds

7.

Xuhua Xia
Published by Springer (2007)
ISBN 10: 0387713360 ISBN 13: 9780387713366
New Hardcover Quantity Available: 1
Seller:
Books Express
(Portsmouth, NH, U.S.A.)

Book Description Springer, 2007. Hardcover. Condition: New. 2007. Ships with Tracking Number! INTERNATIONAL WORLDWIDE Shipping available. Buy with confidence, excellent customer service!. Seller Inventory # 0387713360n

More information about this seller | Contact this seller

Buy New
312.98
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds