Testosterone: Action, Deficiency, Substitution - Hardcover

 
9780387642833: Testosterone: Action, Deficiency, Substitution

Synopsis

New developments in testosterone therapy are summarized here by internationally renowned experts. They review both basic and clinical knowledge in fourteen chapters. The book begins with the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs. Three chapters deal with specific aspects of testosterone action, namely its role in spermatogenesis, its psychotropic effects and its effects on bones. Syndromes caused by androgen resistance are described in order to highlight the importance of properly functioning enzymes and receptors in the target organs. Causes and symptoms of male hypogonadism, the major indication for testosterone treatment, are described. Five chapters are devoted to the pharmacology, pharmacokinetics and clinical uses and abuses of testosterone preparations. The new transdermal testosterone application is described in detail. Side effects of testosterone treatment are reviewed. The possible role of androgens in the development of prostatic hypertrophy and carcinoma is discussed extensively since this question is of major concern to the clinician.

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Review

'... I was deeply impressed by the brilliance of selection and organization of topics, their authors, technical format and clear and instructive literary styles, which all result from the excellent editorial work ... The book certainly should be considered an important contribution to understand the contemporary knowledge about testosterone and about androgens in general.' Endocrine Regulations

'This book should be read not only by scientists dealing with steroid hormones but also by every doctor treating patients with androgen deficiency. It presents the current knowledge concerning androgen replacement therapy in a convincing manner.' Blackwell Verlag

'There is much to commend in this book ... an impressive overview.' The Endocrinologist

'This book should be read not only by scientists dealing with steroid hormones but also by every doctor treating patients with androgen deficiency. It presents the current knowledge concerning androgen replacement therapy in a convincing manner.' Andrologia

'... provides a update encyclopedia on testosterone for the years to come. the book is well edited and illustrated and concluded by a detailed index. The volume belongs in the library of all those who deal with men, both clinically and scientifically.' The Aging Male

'This is the third edition of what has become a standard reference work on all things androgenic ... there is much to commend in this book ... it remains an impressive overview of the area and the major changes made since the 1998 version are to the good.' Human Fertility

'This book is a must reference for any practitioner or researcher who is going to be involved with measuring or prescribing testosterone or, for that matter, any androgen. It is so comprehensive that urologists who consider themselves a subspecialist in either oncology, impotence, infertility or geriatrics will find the information in this tome pertinent to their subspecialty.' The Journal of Urology

Book Description

This is an authoritative, reference on testosterone, and its role in human physiology and pathology. It covers biosynthesis, mechanisms of action and reviews effects on brain and behaviour, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and lipids, erection, and the prostate. Therapeutic and contraceptive applications are assessed.

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