This book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans.
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Danilo Lasic , Frank Martin
Examining all aspects of stealth liposomes, this book provides a historical perspective, describes liposome behavior in biological systems, and a reviews the role of glycolipid-containing liposome systems. It presents theoretical considerations followed by contributions that provide experimental verification of the various theoretical models and discusses chemistry, biology, and pharmacology. Topics include the use of sterically stabilized liposomes loaded with anticancer agent doxorubican in humans, preclinical studies in various tumors, sterically stabilized liposomes with attached antibodies, and other applications.
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