New Insights on the Development of the Vascular System - Softcover

Ribatti

Softcover

ISBN 10: 0323905994 ISBN 13: 9780323905992

Publisher: Academic Press, 2022

Synopsis

New Insights on the Development of the Vascular System examines the most recent literature and data on the development of the vascular system, along with advice on new laboratory techniques and approaches to data analysis. This volume is a comprehensive handbook to the state-of-the-art in vascular system development. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system, and there is extensive literature on the genetic background and molecular mechanisms responsible for blood vessel formation. Yet new data and techniques have been developed in recent years.

Although scientific literature covers the descriptive aspects of embryonic vascular system development, modern techniques such as the technology of cell fusion, cell sorting and image analysis give new insight into the mechanisms by which vessels form and regress and how blood flow changes directions in the same vessels.

• Gives a comprehensive overview of the most recent literature in the field of vascular system development
• Presents new data, including sections on endothelial cell signaling and technologies of cell fusion, cell sorting and image analysis
• Provides useful insights on the analysis of new experimental work
• Suggests modern techniques for scientists to use in the lab
• Gives an overview of vascular biology that will be useful for those needing rapid familiarity
• Provides an expert guide to the state-of-the-art in vascular system development as written by a leader in the field

About this title

About the Author

Domenico Ribatti was awarded his M.D. degree in October 1981, with full marks. In 1983, D.R. joined the Medical School as Assistant at the Institute of Human Anatomy, University of Bari. In 1984, he took the specialization in Allergology. In 1989, he spent one year in Geneva, working at the Department of Morphology (Prof. R. Montesano). In 2008, he received the honoris causa degree in Medicine and Pharmacy form the University of Timisoara (Romania). D.R. is author of 866 publications as reported in PUBmed and contributed to 50 chapters to books. Overall, his papers have been cited 51153 times.

He has published many books with both Elsevier and Springe

From the Back Cover

Several genetic and epigenetic mechanisms are involved in the early development of the vascular system, and there is extensive literature on the genetic background and the molecular mechanisms responsible for blood vessel formation. Yet new data and techniques have been developed in recent years. For example, evidence is emerging that blood vessels themselves have the ability to provide instructive regulatory signals to surrounding non-vascular target cells during organ development. Endothelial cell signaling is believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodeling. Although scientific literature covers descriptive aspects of embryonic vascular system development, modern techniques such as the technology of cell fusion, cell sorting and image analysis, give new insight into the mechanisms by which vessels form and regress and blood flow changes directions in the same vessels, offering powerful tools for examining the development of the vascular system. New Insights on the Development of the Vascular System examines the most recent literature and data on the development of the vascular system, as well as offering advice on new laboratory techniques and approaches to data analysis. This volume is a comprehensive handbook to the state-of-the-art in vascular system development.

Edition details

• Publisher: Academic Press
• Publication date: 2022
• Language: English
• ISBN 10: 0323905994
• ISBN 13: 9780323905992
• Binding: Paperback
• Edition number: 1
• Number of pages: 124