The Vitamins: Fundamental Aspects in Nutrition and Health, Sixth Edition presents both overviews and in-depth discussions of the sources, chemistry, metabolism and functions of these essential nutrients in physiology and health. Sections cover perspectives (history of discovery, general properties and impacts), individual Vitamins (their respective chemistries, metabolism), and their dietary sources and global needs. In addition, the inclusion and interpretation of recent clinical research findings relevant to all vitamins, particularly vitamins A, D, E, K, C, thiamin, folate and vitamin B12 is included, along with an expanded discussion on single-carbon metabolism), implications to neuropathies, and more.
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Gerald F. Combs, Jr. is an internationally recognized leader in nutrition, particularly in the areas of micronutrient functions, diet and cancer prevention, and sustainable food systems. He has conducted research ranging from fundamental studies with cultured cells and animal models to human metabolic and clinical investigations, including studies in China, Bangladesh, Costa Rica and Malawi. He has lectured in some 30 countries and published more than 350 scientific papers and reviews, and 15 books, including six editions of The Vitamins: Fundamental Aspects in Nutrition and Health. He received his graduate training in nutritional biochemistry at Cornell University, where he later served on that faculty for 29 years before being named Director of the USDA Human Nutrition Research Center in Grand Forks ND from 2020-2015. He was is a Senior Scientist at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston, 2015-2022. He presently is Professor Emeritus, Div. Nutritional Sciences, at Cornell University.
James P. McClung completed his B.S. and M.S. degrees at the University of New Hampshire, and his doctoral degree at Cornell University. He completed a National Research Council post-doctoral fellowship prior to assuming a career in Nutrition Science with the Department of Defense. Dr. McClung’s research has focused on micronutrient nutrition at both the basic and applied levels and has led to the fielding of applied solutions for the optimization of human health and performance. He is an active member of a number of professional societies, including the American Society for Nutrition. He has authored or co-authored over 100 peer reviewed manuscripts, technical reports, and book chapters, and has served on the editorial boards of a number of leading international nutrition journals. Dr. McClung has co-authored the two most recent editions of The Vitamins: Fundamental Aspects in Nutrition and Health.
The Vitamins: Fundamental Aspects in Nutrition and Health, Sixth Edition presents both overviews and in-depth discussions of the sources, chemistry, metabolism and functions of these essential nutrients in physiology and health. Originally written 30 years ago as an upper level collegiate text, this will be the sixth edition of what has become the recognized the reference in the fields of nutrition and food science.
The Vitamins: Fundamental Aspects in Nutrition and Health, Sixth Edition is comprised of three thematic sections: Perspectives (history of discovery, general properties and impacts of deficiencies and excess); the Individual Vitamins (their respective chemistries, metabolism and metabolic functions); and the Use of this Current Knowledge (dietary sources, global needs, assessment of vitamin status). Chapters will include introductory lists of vocabulary subsequently defined in context in each chapter, case studies, recent developments, data, decision trees, and text boxes.
The sixth edition of this widely used reference text will build upon previous editions with updating, as well as specific emphases on: the inclusion and interpretation of recent clinical research findings relevant to all vitamins, and particularly vitamins A, D, E, K, C, thiamin, folate and vitamin B12.; expanded discussion of single-carbon metabolism (and roles of folate, vitamin B12 and choline) and implications to neuropathies, including impact of folate fortification on disease; expanded discussion of the global prevalence of vitamin deficiencies, particularly those of vitamin D and thiamin; discussion of roles of vitamins in inflammation and immunity as a cross-cutting theme; expanded discussion of enteric microbial biosynthesis of vitamins (particularly vitamin K) as a cross-cutting theme; discussion of nutrigenomic and nutrigenetic aspects of vitamins; discussion of polymorphisms of enzymes involved in vitamin metabolism and implication to physiological function; discussion of ‘silent’ vitamin deficiencies (those leading to asymptomatic metabolic impairment), particularly those of thiamin, riboflavin, niacin and pyridoxine; and discussion of latest research on dietary patterns and their implications to vitamin status.
As the only comprehensive reference text on the vitamins, The Vitamins: Fundamental Aspects in Nutrition and Health, Sixth Edition fills a need not addressed by the several large, general nutrition texts of which the vitamins comprise only a portion. This sixth edition is designed to support advanced instruction on the subject, and also to provide both metabolic detail plus key recent research findings that have been pivotal in shaping understanding of the roles of this class of essential nutrients in the health of humans and other animals. The book’s extensive listings of vitamin requirements of humans and animals, as well as the vitamin contents of foods and feedstuffs, enhance its utility for teaching, learning and use as a reference tool.
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