Environmental Neuroscience: Advancing the Understanding of How Chemical Exposures Impact Brain Health and Disease: Proceedings of a Workshop (Environmental Health Matters Initiative) - Softcover

National Academies Of Sciences, Engineering, And Medicine; Division On Earth And Life Studies; Health And Medicine Division; Board On Environmental Studies And Toxicology; Board On Health Sciences Policy; Forum On Neuroscience And Nervous System Disorders

Softcover

ISBN 10: 0309683092 ISBN 13: 9780309683098

Publisher: National Academies Press, 2020

Synopsis

Humans are potentially exposed to more than 80,000 toxic chemicals in the environment, yet their impacts on brain health and disease are not well understood. The sheer number of these chemicals has overwhelmed the ability to determine their individual toxicity, much less potential interactive effects. Early life exposures to chemicals can have permanent consequences for neurodevelopment and for neurodegeneration in later life. Toxic effects resulting from chemical exposure can interact with other risk factors such as prenatal stress, and persistence of some chemicals in the brain over time may result in cumulative toxicity. Because neurodevelopmental and neurodegenerative disorders - such as attention-deficit hyperactivity disorder and Parkinson's disease - cannot be fully explained by genetic risk factors alone, understanding the role of individual environmental chemical exposures is critical.

On June 25, 2020, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders hosted a workshop to lay the foundation for future advances in environmental neuroscience. The workshop was designed to explore new opportunities to bridge the gap between what is known about the genetic contribution to brain disorders and what is known, and not known, about the contribution of environmental influences, as well as to discuss what is known about how genetic and environmental factors interact. This publication summarizes the presentation and discussion of the workshop.

Edition details

• Publisher: National Academies Press
• Publication date: 2020
• Language: English
• ISBN 10: 0309683092
• ISBN 13: 9780309683098
• Binding: Paperback
• Number of pages: 86