Review of DOD's Approach to Deriving an Occupational Exposure Level for Trichloroethylene (The National Academies of Sciences Engineering Medicine: Consensus Study) - Softcover

National Academies Of Sciences, Engineering, And Medicine; Division On Earth And Life Studies; Board On Environmental Studies And Toxicology; Committee To Review DOD's Approach To Deriving An Occupational Exposure Limit For TCE

 
9780309499248: Review of DOD's Approach to Deriving an Occupational Exposure Level for Trichloroethylene (The National Academies of Sciences Engineering Medicine: Consensus Study)
Softcover
ISBN 10: 0309499240 ISBN 13: 9780309499248
Publisher: National Academies Press, 2019

Synopsis

Trichloroethylene (TCE) is a solvent that is used as a degreasing agent, a chemical intermediate in refrigerant manufacture, and a component of spot removers and adhesives. It is produced in mass quantities but creates dangerous vapors and is an environmental contaminant at many industrial and government facilities, including facilities run by the U.S. Department of Defense (DoD). It is important to determine the safe occupational exposure level (OEL) for the solvent in order to protect the health of workers who are exposed to its vapors. However, there are concerns that the current occupational standards insufficiently protect workers from these health threats.

Review of DOD's Approach to Deriving an Occupational Exposure Level for Trichloroethylene makes recommendations to improve the DoD's approach to developing an OEL for TCE, strengthen transparency of the process, and improve confidence in the final OEL value. This report reviews the DoD's approach using a literature review, evidence synthesis based on weight of evidence [WOE], point-of-departure derivation, physiologically based pharmacokinetic modeling, extrapolation tools, and explores other elements of the process of deriving an OEL for TCE. It examines scientific approaches to developing exposure values and cancer risk levels, defining the scope of the problem, and improving hazard identification.

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Publisher
National Academies Press
Publication date
2019
Language
English
ISBN 10 
0309499240
ISBN 13 
9780309499248
Binding
Paperback
Number of pages
76