A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been revised by a committee of experts, based on input from scientists and the public. The Guide incorporates recent research on commonly used species, including farm animals, and contains extensive references. It is organised around major components of animal use: · Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. · Animal care and use programme. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee; regulatory considerations; personnel management (including qualifications, training, and occupational health and safety); and programme oversight. · Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventative medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. · Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialised facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policymakers involved in research issues, and animal welfare advocates.
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Institute of Laboratory Animal Research, Commission on Life Sciences, National Research Council
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