Health Risks from Dioxin and Related Compounds: Evaluation of the EPA Reassessment - Softcover

National Research Council; Division On Earth And Life Studies; Board On Environmental Studies And Toxicology; Committee On EPA's Exposure And Human Health Reassessment Of TCDD And Related Compounds

Softcover

ISBN 10: 0309102588 ISBN 13: 9780309102582

Publisher: National Academies Press, 2006

Synopsis

Although the U.S. Environmental Protection Agency presented a comprehensive review of the scientific literature in its 2003 draft reassessment of the risks of dioxin, the agency did not sufficiently quantify the uncertainties and variabilities associated with the risks, nor did it adequately justify the assumptions used to estimate them, according to this new report from the National Academies' National Research Council. The committee that wrote the report recommended that EPA re-estimate the risks using several different assumptions and better communicate the uncertainties in those estimates. The agency also should explain more clearly how it selects both the data upon which the reassessment is based and the methods used to analyze them.Table of Contents

• Front Matter
• Public Summary
• Summary
• 1 Introduction
• 2 General Considerations of Uncertaintyand Variability, Selection of DoseMetric, and Dose-Response Modeling
• 3 Toxic Equivalency Factors
• 4 Exposure Assessment
• 5 Cancer
• 6 Noncancer End Points
• 7 Review of Risk Characterization
• 8 Conclusions and Recommendations
• References
• A Biographical Information onCommittee Members
• B EPA's 2005 Guidelines forCarcinogen Risk Assessment

About this title

About the Author

Committee on EPA's Exposure and Human Health Reassessment of TCDD and Related Compounds, National Research Council

Edition details

• Publisher: National Academies Press
• Publication date: 2006
• Language: English
• ISBN 10: 0309102588
• ISBN 13: 9780309102582
• Binding: Paperback
• Number of pages: 268