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9780309096126: Catalyzing Inquiry at the Interface of Computing and Biology

Synopsis

Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.Table of Contents

  • Front Matter
  • Executive Summary
  • 1 Introduction
  • 2 21st Century Biology
  • 3 On the Nature of Biological Data
  • 4 Computational Tools
  • 5 Computational Modeling and Simulation as Enablers for Biological Discovery
  • 6 A Computational and Engineering View of Biology
  • 7 Cyberinfrastructure and Data Acquisition
  • 8 Biological Inspiration for Computing
  • 9 Illustrative Problem Domains at the Interface of Computing and Biology
  • 10 Culture and Research Infrastructure
  • 11 Conclusions and Recommendations
  • A The Secrets of Life: A Mathematician’s Introduction to Molecular Biology
  • B Challenge Problems in Bioinformatics and Computational Biology from Other Reports
  • C Biographies of Committee Members and Staff
  • D Workshop Participants
  • What Is CSTB?

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John C. Wooley and Herbert S. Lin, Editors, Committee on Frontiers at the Interface of Computing and Biology, National Research Council

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National Research Council, Division on Engineering and Physical Sciences, Computer Science and Telecommunications Board, Committee on Frontiers at the
Published by National Academies Press, 2006
ISBN 10: 030909612X ISBN 13: 9780309096126
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National Research Council, Division on Engineering and Physical Sciences, Computer Science and Telecommunications Board, Committee on Frontiers at the
Published by National Academies Press, 2006
ISBN 10: 030909612X ISBN 13: 9780309096126
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Biology, Committee on Frontiers at the Interface of Computing and & National Research Council; Woole
Published by National Academies Press, 2005
ISBN 10: 030909612X ISBN 13: 9780309096126
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