Ethical Conduct of Clinical Research Involving Children - Hardcover

Institute Of Medicine; Board On Health Sciences Policy; Committee On Clinical Research Involving Children

Hardcover

ISBN 10: 0309091810 ISBN 13: 9780309091817

Publisher: National Academies Press, 2004

Synopsis

In recent decades, advances in biomedical research have helped save or lengthen the lives of children around the world. With improved therapies, child and adolescent mortality rates have decreased significantly in the last half century. Despite these advances, pediatricians and others argue that children have not shared equally with adults in biomedical advances. Even though we want children to benefit from the dramatic and accelerating rate of progress in medical care that has been fueled by scientific research, we do not want to place children at risk of being harmed by participating in clinical studies. Ethical Conduct of Clinical Research Involving Children considers the necessities and challenges of this type of research and reviews the ethical and legal standards for conducting it. It also considers problems with the interpretation and application of these standards and conduct, concluding that while children should not be excluded from potentially beneficial clinical studies, some research that is ethically permissible for adults is not acceptable for children, who usually do not have the legal capacity or maturity to make informed decisions about research participation. The book looks at the need for appropriate pediatric expertise at all stages of the design, review, and conduct of a research project to effectively implement policies to protect children. It argues persuasively that a robust system for protecting human research participants in general is a necessary foundation for protecting child research participants in particular.

About this title

About the Author

Marilyn J. Field and Richard E. Berman, Editors, Committee on Clinical Research Involving Children

Edition details

• Publisher: National Academies Press
• Publication date: 2004
• Language: English
• ISBN 10: 0309091810
• ISBN 13: 9780309091817
• Binding: Hardcover
• Number of pages: 445
• Editor: Behrman Richard E., Field Marilyn J.