Cellular Peptidases in Immune Functions and Diseases 2: 477 (Advances in Experimental Medicine and Biology, 477) - Hardcover

Hardcover

ISBN 10: 0306463830 ISBN 13: 9780306463839

Publisher: Springer, 2000

Synopsis

Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.

Edition details

• Publisher: Springer
• Publication date: 2000
• Language: English
• ISBN 10: 0306463830
• ISBN 13: 9780306463839
• Binding: Hardcover
• Number of pages: 537
• Editor: Langner Jürgen, Ansorge Siegfried