Proceedings of the 1993 Biomedical Simulations Research Workshop, held in Los Angeles, California, May 21-22, 1993
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Comprises 13 chapters, arranged into four sections: pharmacokinetics, pharmacodynamics, pharmacometrics, and pharmacotherapeutics. Topics include the application of disposition decomposition analysis to metabolite kinetics; modeling multiple pharmacodynamic end points; new approaches to self-modeling nonlinear regression; and the pharmacokinetic an
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