Proceedings of a Workshop Held in Honolulu, Hawaii, September 19-24, 1992: Structure and Function: v. 357 (Advances in Experimental Medicine and Biology) - Hardcover

Hardcover

ISBN 10: 0306447347 ISBN 13: 9780306447341

Publisher: Kluwer Academic / Plenum Publishers, 1994

Synopsis

Three-Dimensional Structure of Lactoferrin in Various Functional States.- Characterization of Two Kinds of Lactotransferrin (Lactoferrin) Receptors on Different Target Cells.- Primary and Three-Dimensional Structure of Lactotransferrin (Lactoferrin) Glycans.- Synergism and Substitution in the Lactoferrins.- Salt Effects on the Physical Properties of the Transferrins.- Interaction of Lactoferrin with Sequestered Transition Metal Ions.- Bactericidal Activity of Different Forms of Lactoferrin.- The Effects of Lactoferrin on Gram-Negative Bacteria.- Faecal Flora in the Newborn: Effect of Lactoferrin and Related Nutrients.- The Monocytic Receptor for Lactoferrin and Its Involvement in Lactoferrin-Mediated Iron Transport.- Study on the Binding of Lactotransferrin (Lactoferrin) to Human PHA-Activated Lymphocytes and Non-Activated Platelets: Localisation and Description of the Receptor-Binding Site.- Physical Characteristics and Polymerization during Iron Saturation of Lactoferrin, a Myelopoietic Regulatory Molecule with Suppressor Activity.- Lactoferrin and the Inflammatory Response.- The Role of Lactoferrin as an Anti-inflammatory Molecule.- Interaction of Lactoferrin with Mononuclear and Colon Carcinoma Cells.- Lactoferrin Receptors in Intestinal Brush Border Membranes.- Maternal Lactoferrin in the Urine of Preterm Infants: Evidence for Retention of Structure and function.- Lactoferrin Gene Promoter in Human and Mouse: Analogous and Dissimilar Characteristics.- Lactoferrin cDNA: Expression and In Vitro Mutagenesis.- Antimicrobial Peptides of Lactoferrin.- Physicochemical and Antibacterial Properties of Lactoferrin and Its Hydrolysate Produced by Heat Treatment at Acidic pH.- A Comparison of the Three-Dimensional Structures of Human Lactoferrin in Its Iron Free and Iron Saturated Forms.- Bovine Lactoferrin: Isolation and Characterisation of Genomic Regulatory Sequences.- X-Ray Structural Analysis of Bovine Lactoferrin at 2.5 Å Resolution.- Binding of Porcine Milk Lactoferrin to Piglet Intestinal Lactoferrin Receptor.- Lactoferrin-Receptor Interaction: Effect of Surface Exposed Histidine Residues.- Kinetic Parameters for the Heat Denaturation of Bovine Lactoferrin in Milk, and Its Effect on Interaction with Monocytes.- Cloning and Expression of the C-Terminal Lobe of Human Lactoferrin.- Crystallographic Studies on Metal and Anion Substituted Human Lactoferrin.- Proposed Mechanisms for the Involvement of Lactoferrin in the Hydrolysis of Nucleic Acids.- Lactoferrin Promotes Nerve Growth Factor Synthesis/Secretion in Mouse Fibroblast L-M Cells.- Summary Chapter: Lactoferrin Structure and Function: Remaining Questions, Methodological Considerations and Future Directions.

About this title

Synopsis

The 32 papers from a September 1992 international workshop in Honolulu, bring together knowledge about the iron-binding lactoferrin protein, which has been scattered among many disciplines because its biological functions are so widely diverse. They discuss structural features such as its carbohydrate side chains and the capacity to bind different

Edition details

• Publisher: Kluwer Academic / Plenum Publishers
• Publication date: 1994
• Language: English
• ISBN 10: 0306447347
• ISBN 13: 9780306447341
• Binding: Hardcover
• Number of pages: 285
• Editor: Hutchens T. William, Etc.