The short period since the publication of Volume 1 of Methods in Membrane Biology has been a time of momentous progress. Calorimetry, electron spin and nuclear magnetic resonance, X-ray diffraction, and freeze-cleavage electron microscopy, reinforced by biochemical analyses and enzymatic studies, have led to universal acceptance of a generalized membrane model. All membrane biologists would agree that a major element of all biological membranes is a bilayer of phospholipids which, in some instances, also contains other lipids, notably sterols and glycolipids. The fatty acid com- position of the lipids of most membranes is such that the lipids are above their transition temperatures in their normal environment so that the bilayer is fluid. The microviscosity of the fatty acyl groups decreases pro- gressively down the chain so that, at the hydrocarbon interior of the bilayer, the lipid phase has a viscosity approximating that of olive oil at room temperature. As a consequence of this membrane fluidity, a phospholipid molecule is very mobile within the plane of the membrane (moving a distance of about 1-2 fLm in 1 s) but the movement of a phospholipid molecule from one side of the membrane bilayer to the other (flip-flop) is very slow. The lipid bilayer is an essentially inert and rather impermeable struc- ture, as shown by many studies with model systems. Proteins, of course, provide the catalytic components of the membranes. as well as playing a significant structural role.
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Seller: Wonder Book, Frederick, MD, U.S.A.
Condition: Good. Good condition. Good dust jacket. Volume 4. A copy that has been read but remains intact. May contain markings such as bookplates, stamps, limited notes and highlighting, or a few light stains. Seller Inventory # P08A-03085
Seller: Books of Paradise, Magalia, CA, U.S.A.
Hardcover. Condition: Very Good. Dust Jacket Condition: Very Good. First Edition; First Printing. Book has light edgewear, pages lightly toning, top corners of covers slightly bumped, name stamped inside covers; DJ has light shelfwear, mild toning, couple tiny tears w/crease; b/w photos; 298 pages. Seller Inventory # ST858
Seller: Munster & Company LLC, ABAA/ILAB, Corvallis, OR, U.S.A.
Condition: Good. Springer, 1975. Cover lightly rubbed/soiled, corners very lightly rubbed/bumped, spine sunned, spine ends very lightly rubbed/bumped; top edge very lightly soiled and stamped by previous owner, fore/bottom edges very lightly soiled/bumped; previous owner's stamp on front paste down, faint erasures on ffep; binding tight; cover, edges, and interior intact and clean except as noted. hardcover. Good. Seller Inventory # 620763
Seller: Book House in Dinkytown, IOBA, Minneapolis, MN, U.S.A.
Hardcover. Condition: Very Good. Dust Jacket Condition: Good Dust Jacket. Very good hardcover in good dust jacket. Previous owner's inscription on front endpaper and inside front board. Rubbing and some small tears to edges of jacket. A little marker on jacket spine. Seller Inventory # 173702