System Modeling in Cellular Biology – From Concepts to Nuts and Bolts - Softcover

Szallasi, Zoltan; Periwal, Vipal; Stelling, J

Softcover

ISBN 10: 0262514222 ISBN 13: 9780262514224

Publisher: MIT Press, 2010

Synopsis

An introduction and overview of system modeling in biology that is accessible to researchers from different fields, including biology, computer science, mathematics, statistics, physics, and biochemistry.

Research in systems biology requires the collaboration of researchers from diverse backgrounds, including biology, computer science, mathematics, statistics, physics, and biochemistry. These collaborations, necessary because of the enormous breadth of background needed for research in this field, can be hindered by differing understandings of the limitations and applicability of techniques and concerns from different disciplines. This comprehensive introduction and overview of system modeling in biology makes the relevant background material from all pertinent fields accessible to researchers with different backgrounds.

The emerging area of systems level modeling in cellular biology has lacked a critical and thorough overview. This book fills that gap. It is the first to provide the necessary critical comparison of concepts and approaches, with an emphasis on their possible applications. It presents key concepts and their theoretical background, including the concepts of robustness and modularity and their exploitation to study biological systems; the best-known modeling approaches, and their advantages and disadvantages; lessons from the application of mathematical models to the study of cellular biology; and available modeling tools and datasets, along with their computational limitations.

About this title

About the Authors

Zoltan Szallasi is Professor at the Center for Biological Sequence Analysis, Technical University of Denmark.

Jö rg Stelling is a faculty member of the Department of Biosystems Science and Engineering at ETH Zü rich.

Vipul Periwal is with the Mathematical Cell Modeling Section, NIDDK, National Institute of Health.

Edition details

• Publisher: MIT Press
• Publication date: 2010
• Language: English
• ISBN 10: 0262514222
• ISBN 13: 9780262514224
• Binding: Paperback
• Number of pages: 464