This text is designed to provide conceptual outlines and detailed procedures for basic and advanced studies of cell death by apoptosis. Chapters on the recognition of apoptosis, as distinguished from necrosis and nonspecific cell DNA damage, are followed by a systematic examination of the established and the principal novel methodologies utilized by some leading laboratories conducting research on apoptosis. The organization is on the lines of signalling for apoptosis, the apoptotic cascade, and the execution of apoptosis. A wide variety of procedures are provided which will enable the reader to participate in cutting-edge research.
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"The major strength of this book is the wealth of apaptosis-associated protocols provided by the authors ... a significant addition to the apaptosis literature and particularly valuable for mammalian cell biologists" Trends in Cell Biology
George Studzinski is at New Jersey Medical School.
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