The placebo effect is one of the most widely used and familiar terms within science and medicine, yet it is not always clear just what we mean by a placebo effect. Though we might describe a placebo effect as being 'all in the mind', we now know that there is a genuine neurobiological basis to this phenomenon. In recent years our knowledge of the neural bases of the placebo effect has developed markedly, and we now have a far better understanding of how it can influence both the course of a disease and the response to therapy. This is the first book to critically review the mechanisms of placebo and placebo-related effects across all medical conditions, diseases, and therapeutic interventions. It describes the main psychological and biological mechanisms of placebo responsiveness across the entire spectrum of medical disciplines. In addition, it looks at the clinical and ethical implications of administering placebos. Exhaustive in its coverage, and written by a world authority in the field, this is the definitive reference text to the placebo effect - one that will be essential for researchers and clinicians across a wide range of medical specialities.
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Benedetti is highly analytical in his approach and, at the same time, has the ability to explain complex matters so that they are easily understood. This book should be a must for all who struggle to make sense out of the intriguing phenomenon we call placebo. (Pharmaceutical Press)
Benedetti's book is a lucid and extensive review entrenched in the neuroscience of placebo research and heralding the importance of this area of study. (PsycCRITIQUIES)
... comprehensive and thoughtful volume ... All physicians could learn much from this volume. (New England Journal of Medicine)
The breadth of topics addressed ... make this book an important read for anyone in the medical field. (Journal of the Neurological Sciences)
Highly commended in the Medicine Category of the BMA Book Awards 2009
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