Cancer Biology - Hardcover

Ruddon, Raymond W.

Hardcover

ISBN 10: 0195096908 ISBN 13: 9780195096903

Publisher: Oxford University Press Inc, 1995

Synopsis

A thorough yet concise account of cancer biology, this book emphasises the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It also defines the fundamental pathophysiological changes that occur in tumor tissue and in the host animal or patient. The approach throughout the book is to discuss the historical development of a field, citing the key experimental advances to the present day, and to evaluate the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behavior. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well illustrated with schematic diagrams and actual research data to demonstrate points made in the text, and there is an extensive, up-to-date bibliography. In this revision, Dr. Ruddon has organized his text to provide more integrated discussion of the many topics covered in the third edition,. . At the same time, he has included much new material on molecular genetics and genetic diagnosis (e.g., DNA microarrays to mark tumors), RNA interference, stem cells, cell cycle regulation, angiogenesis, etc.

About this title

Review

From reviews of previous editions: "Highly recommended for readers who wish to spend several hours with a well-written, well-selected, effectively illustrated, and well-integrated overview of the sciences that join to make up the field of tumor biology." --New England Journal of Medicine"I can think of no better introduction for a graduate student to contemporary cancer research, especially at the cellular level." --The Times Higher Education Supplement From reviews of previous editions: "Highly recommended for readers who wish to spend several hours with a well-written, well-selected, effectively illustrated, and well-integrated overview of the sciences that join to make up the field of tumor biology." --New England Journal of Medicine "I can think of no better introduction for a graduate student to contemporary cancer research, especially at the cellular level." --The Times Higher Education Supplement From reviews of previous editions: "Highly recommended for readers who wish to spend several hours with a well-written, well-selected, effectively illustrated, and well-integrated overview of the sciences that join to make up the field of tumor biology." --New England Journal of Medicine "I can think of no better introduction for a graduate student to contemporary cancer research, especially at the cellular level." --The Times Higher Education Supplement From reviews of previous editions: "Highly recommended for readers who wish to spend several hours with a well-written, well-selected, effectively illustrated, and well-integrated overview of the sciences that join to make up the field of tumor biology." --New England Journal of Medicine"I can think of no better introduction for a graduate student to contemporary cancer research, especially at the cellular level." --The Times Higher Education Supplement

Edition details

• Publisher: Oxford University Press Inc
• Publication date: 1995
• Language: English
• ISBN 10: 0195096908
• ISBN 13: 9780195096903
• Binding: Hardcover
• Edition number: 3
• Number of pages: 544