Protein kinase plays a major role in cellular function and regulation. This enzyme regulates many cellular processes, including signal transduction, intracellular pH, ion channel activity, cell transformation, tumorigenesis and apoptosis. In addition to involvement in cellular processes, the molecular and regulatory properties of the enzyme are discussed. The chapters are written by experts and include careful documentation of up-to-date research. Biochemists, pharmacologists, physiologists and cell biologists need to understand the role of this enzyme because it is involved in so many diverse biological functions. The subject is complex and difficult and this book will provide a useful overview and perspective on this active field.
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"Does a masterful job of tying various themes together and comprehensively covering and citing literature so that the reader can pursue the relationship of pkC to whatever signal transduction pathway(s) is of interest....A valuable resource. It is a vast compilation of research." --The Physiologist"For investigators hoping to sample the involvement of PKC in physiological processes, Kuo, a pioneer in PKC studies, has assembled a welcome source."--Trends in Cell Biology
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