Membrane Protein Structure: Experimental Approaches: No.1 (American Physiological Society Methods in Physiology S.) - Hardcover

White, Stephen H.

Hardcover

ISBN 10: 0195071123 ISBN 13: 9780195071122

Publisher: Oxford University Press Inc, 1994

Synopsis

Studies of receptors, ion channels, and other membrance proteins reuire a solid understanding of their structural principles. Membrane protein structure, however, is one of the most challenging fields of structural biology. The structures of only three types of transmembrance proteins have been determined to moderate or high resolution during a two-decade period in which the amino acid sequence of hundreds, if not thousands, of membrane proteins have been reported. As a result, the creation of hypothetical structural models to serve as guides for studies of receptors, channels, and other membrance proteins has become crucially important to progress. But the development of suitable models requires an understanding of protein structure and structure-prediction methods as well as membrane biophysics and lipid physical chemsitry. Because the literature in each of these fields is expanding rapidly and can be daunting even for the experts, this book has been organized to share the experiences of some of the experts with researchers who need to know about the critical issues of membrane protein strcture. This book is intended for physiologists, biophysicists, biochemists, cell biologists.

Edition details

• Publisher: Oxford University Press Inc
• Publication date: 1994
• Language: English
• ISBN 10: 0195071123
• ISBN 13: 9780195071122
• Binding: Hardcover
• Number of pages: 405