Protein Stability and Stablization Through Protein Engineering (Ellis Horwood Series in Biochemistry and Biotechnology) - Hardcover

Nosoh, Y.; Sekiguchi, T.

Hardcover

ISBN 10: 0137217889 ISBN 13: 9780137217885

Publisher: Ellis Horwood Ltd , Publisher, 1991

Synopsis

Dealing with the relationship between protein stability and stabilization via protein engineering, this book emphasizes the mechanism of protein stability, the procedures of protein stabilization, and the mechanism and control of protein stability through protein engineering. Opening by providing the necessary background on protein structure required for a full understanding of the mechanism of protein stability and the strategy of protein stabilization, the author reviews the mechanisms of protein stability showing how the bonds and interactions participate in constructing the stable, but delicate, structure of proteins, and how protein stability can be explained from a molecular or physiochemical basis. There is coverage of the stable enzymes (widely employed in various fields of protein chemistry) which reveal the mechanism of stability and the unfolding of proteins. The efficacy of these enzymes is debated. The immobilization of enzymes and cells is discussed, together with the extreme stability of some enzymes in organic solvents. Classic strategy, employed to stabilize proteins, is reviewed.

The final chapter deals with the most promising strategy for protein stabilization - protein engineering.

Edition details

• Publisher: Ellis Horwood Ltd , Publisher
• Publication date: 1991
• Language: English
• ISBN 10: 0137217889
• ISBN 13: 9780137217885
• Binding: Hardcover
• Number of pages: 180