Neurological Disorders: Novel Experimentation and Therapeutic Strategies (Ellis Horwood series in neuroscience) - Hardcover

Vecsei, Laszlo; Etc.

Hardcover

ISBN 10: 0136171842 ISBN 13: 9780136171843

Publisher: Ellis Horwood Ltd , Publisher, 1991

Synopsis

Providing a summary of some of the recent exciting discoveries and new technologies in neuroscience which are the most likely candidates to influence the future therapeutic strategies of neurological disorders, this book has been aimed at those studying and working in the area of neuroscience. The book discusses the potential to transfer genes into neurones - which allows for the possibility of performing gene therapy to treat neurological disease. A biocompetitive polymeric matrix system which permits the sustained and localized release of neuroactive substances directly into the brain, is discussed. Material is included on cell replacement therapy by foetal tissue transplantation which may prove an efficient approach in the treatment of neurological disorders. The book discusses the potential usefulness of molecular replacement with NGF, gangliosides, somatostatin and some other peptides. A review of the modification of cerebral excitatory amino acid metabolism as a potential therapeutic benefit in the treatment of various neurological illnesses is included.

The book also examines the unique opportunities provided by microdialysis in investigating local brain metabolic processes, including the metabolic changes after gene-therapy or implantation of polymeric matrix, the function of foetal tissue transplants or local excitatory amino acid metabolism.

Edition details

• Publisher: Ellis Horwood Ltd , Publisher
• Publication date: 1991
• Language: English
• ISBN 10: 0136171842
• ISBN 13: 9780136171843
• Binding: Hardcover
• Edition number: 1
• Number of pages: 300