Electroanalytical Applications of Quantum Dot-Based Biosensors (Micro and Nano Technologies) - Softcover

Softcover

ISBN 10: 0128216700 ISBN 13: 9780128216705

Publisher: Elsevier, 2021

Synopsis

Quantum dots (QDs) are hybrid organic/inorganic nanoparticles with novel physical properties. QDs have two components: an inorganic core and an optically active coated shell. Moreover, surface coatings can be applied to QDs to modify the particle as needed for experiments. Hydrophilic coatings prevent leaking of metal cargo from the core, enhancing the solubility in biological contexts and bind molecules, such as receptor–ligands, antibodies, therapeutic, and diagnostic macromolecules for enhanced effects. Their high surface-to-volume ratio allows multiple functional groups to attach onto the surface of the particles at constant surface volume. Silicon-, gallium-, indium-, or germanium-based; cadmium-based; and carbon-based QDs have already been used in many applications, such as imaging probes for the engineering of multifunctional nanodevices. Superior properties of QDs make them an excellent system in technology and biotechnology.

This book describes electroanalytical applications of QD-based nanobiosensors, including brief information about the synthesis and characterization of QDs and basics of electroanalytical methods, followed by QDs in electrochemical biomimetic sensors, QDs in microchips, inorganic materials doped QDs, QD-based electrochemical DNA biosensors, electroluminescence for biomarker analysis using aptamer-based QDs, QD-based photoelectrochemical techniques, enzyme-based nanobiosensors using QDs, QD-based electrochemical immunosensors, and QD-modified nanosensors in drug analysis.

• Outlines QD-based applications for drug, food, clinical, and environmental science
• Shows how the properties of QDs make them effective ingredients in biosensing applications
• Assesses the major challenges in integrating QDs in biosensing systems

About this title

About the Author

Bengi Uslu is Professor of Analytical Chemistry, at Ankara University, Faculty of Pharmacy, Turkey. Her research interests include Electrochemistry, HPLC, Drug Analysis, Redox Mechanisms of Drug Active Compounds, Spectrophotometry, and Biosensors.

From the Back Cover

Quantum dots are hybrid organic/inorganic nanoparticles with novel physical properties. Quantum dots have two components: an inorganic core and optically active coated shell. Moreover, surface coatings can be applied to quantum dots to modify the particle as needed for experiments. Hydrophilic coatings prevent leaking of metal cargo from the core, enhancing the solubility in biological contexts and bind molecules such as receptor–ligands, anti-bodies, therapeutic and diagnostic macromolecules for enhanced effects. Their high surface-to-volume ratio allows multiple functional groups to attach onto the surface of the particles at constant surface-volume. Silicon-, gallium-, indium- or germanium-based, cadmium-based and carbon-based quantum dots etc. have already been used in many applications such as imaging probes for the engineering of multifunctional nanodevices. Superior properties of quantum dots make them an excellent system in technology and biotechnology.

This book describes electroanalytical applications of quantum-dot based sensors, including protein-ligand interactions, molecularly imprinted polymer-based nanosensors, electrochemical DNA biosensors, electroluminescence for biomarker analysis, photoelectrochemical techniques, enzyme based nanobiosensors, electrochemical immunosensors, and quantum dot modified nanosensors in drug analysis.

This book is an important reference source for materials scientists and engineers who are looking to increase their understanding of how quantum dots are being used to create new types of sensor.

Edition details

• Publisher: Elsevier
• Publication date: 2021
• Language: English
• ISBN 10: 0128216700
• ISBN 13: 9780128216705
• Binding: Paperback
• Number of pages: 476
• Editor: Uslu Bengi