Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach - Softcover

Suki

Softcover

ISBN 10: 0128197161 ISBN 13: 9780128197165

Publisher: Academic Press, 2021

Synopsis

Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces biomechanics and biophysics with applications to understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behavior from the scale of single molecules, through fibrils and fibers, to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. The book introduces the properties and organization of extracellular matrix components and quantitative models of the matrix, and guides the reader through predicting functional properties. 

This book integrates evolutionary biology with multiscale structure to quantitatively understand the function of the extracellular matrix. This approach allows a fresh look into normal functioning as well as the pathological alterations of the extracellular matrix. Professor Suki’s book is written to be useful to undergraduates, graduate students, and researchers interested in the quantitative aspects of the extracellular matrix. Researchers working in mechanotransduction, respiratory and cardiovascular mechanics, and multiscale biomechanics of tendon, cartilage, skin, and bone may also be interested in this book.

• Examines the evolutionary origins and consequences of the extracellular matrix
• Delivers the first book to quantitatively treat the extracellular matrix as a multiscale system
• Presents problems and a set of computational laboratory projects in various chapters to aid teaching and learning
• Provides an introduction to the properties and organization of the extracellular matrix components

About this title

About the Author

He earned an MS in physics (1982) and PhD in biomechanics and respiratory physiology (1987). He is now a professor of Biomedical Engineering at Boston University. Over the last 3 decades, he has worked in various areas of the life sciences including respiratory and vascular physiology and biomechanics, cell and tissue mechanics, computational fluid and solid mechanics applied to various physiological problems and complexity in physiology and biology. He has published over 230 papers, reviews and book chapters. He developed 3 relevant courses: 1) Structure and function of the extracellular matrix (BE 549); 2) Respiratory and cardiovascular engineering (BE 508); and 3) Nonlinear systems in biomedical engineering (BE 567).

From the Back Cover

Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces the basic concepts of biomechanics and biophysics with applications, to better understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behaviour from the scale of single molecules, through fibrils and fibers to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. It provides an introduction to the properties and organization of the extracellular matrix components, to quantitative models of the matrix and guides the reader through predicting the functional properties.

This book integrates evolutionary biology with multiscale structure to quantitatively understand the function of the extracellular matrix. This approach allows a fresh look into the normal functioning as well as the pathological alterations of the extracellular matrix. Prof Suki’s book is written to be useful to upper class undergraduates, graduate students and researchers interested in the quantitative aspects of the extracellular matrix. Researchers working in mechanotransduction, respiratory and cardiovascular mechanics, and multiscale biomechanics of tendon, cartilage, skin and bone may also be interested in this book.

Edition details

• Publisher: Academic Press
• Publication date: 2021
• Language: English
• ISBN 10: 0128197161
• ISBN 13: 9780128197165
• Binding: Paperback
• Number of pages: 282