Chromatin: Structure and Function - Softcover

Wolffe, Alan P.

Softcover

ISBN 10: 0127619151 ISBN 13: 9780127619156

Publisher: Academic Press, 1999

Synopsis

The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and concise fashion, with 60 new illustrations. Chromatin: Structure and Function provides the reader with a concise and coherent account of the nature, structure, and assembly of chromatin and its active involvement in the processes of DNA transcription, replication and repair. This book consistently interrelates the structure of eukaryotic DNA with the nuclear processes it undergoes, and will be essential reading for students and molecular biologists who want to really understand how DNA works.

About this title

About the Author

Alan P. Wolffe is Chief of the Laboratory of Molecular Embryology and of the Section on Molecular Biology at the National Institute of Child Health and Human Development. He was educated in the UK, studying biochemistry at Oxford and completing graduate research with the Medical Research Council in London before moving to the United States. After a post-doctoral fellowship funded by the European Molecular Biology Organization at the Carnegie Institution of Washington, Dr. Wolffe joined the National Institutes of Health in 1988. His research interests include the earliest events in vertebrate development, with respect to the mechanisms through which nucleic acid binding proteins influence gene expression.

From the Back Cover

Chromatin is the basic structural matrix of the eukaryotic chromosome and understanding its structure and function is essential to fully comprehend the mechanisms of gene regulation and the replication and recombination of DNA in higher organisms.
This Third Edition ofChromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. Also featured in this third edition are 60 new illustrations.
Written in a clear and concise fashion, Chromatin: Structure and Function is essential reading for advanced undergraduates, postgraduates and newcomers to the fields of biochemistry, cell biology, and molecular genetics.

Edition details

• Publisher: Academic Press
• Publication date: 1999
• Language: English
• ISBN 10: 0127619151
• ISBN 13: 9780127619156
• Binding: Paperback
• Edition number: 3
• Number of pages: 464