The SV40 Replicon Model for Analysis of Anticancer Drugs (Biotechnology Intelligence Unit) - Hardcover

Snapka, Robert M.

Hardcover

ISBN 10: 0126536309 ISBN 13: 9780126536300

Publisher: Academic Press, 1996

Synopsis

This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments.

• Presents unique advantages of SV40 as an experimental system for the study of classes of anticancer drugs
• Details new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication
• Provides details to help the reader design and interpret similar experiments

About this title

About the Author

Dr. Snapka is an associate professor of Radiology at The Ohio State University, teaching courses in Radiation Biology, DNA Tumor Viruses, Drug Resistance, and Genetic Instability. Dr. Snapka earned his B.S. in Biology and M.S. in Chemistry at North Texas State University. He earned his Ph.D. at the University of California, Irvine and worked as a Research Fellow at the University of California, Berkeley and Massachusetts Institute of Technology. He is the author of over 35 article in refereed journals and is currently conducting research in anticancer drug resistance and drug discovery.

From the Back Cover

This volume of the Biotechnology Intelligence Unit series reviews the history of SV40 as a mammalian replicon model and covers the techniques used to analyze viral DNA replication.

Edition details

• Publisher: Academic Press
• Publication date: 1996
• Language: English
• ISBN 10: 0126536309
• ISBN 13: 9780126536300
• Binding: Hardcover
• Number of pages: 200