Development of the Nervous System - Hardcover

Sanes, Dan H.; Reh, Thomas A.; Harris, William A.

Hardcover

ISBN 10: 0126186219 ISBN 13: 9780126186215

Publisher: Academic Press, 2005

Synopsis

Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology.

• Updates information including all the new developments made in the field since the first edition
• Now in full color throughout, with the original, artist-rendered drawings from the first edition completely redone, revised, colorized, and updated

About this title

About the Authors

Dr. Sanes is Professor in the Center for Neural Science and Department of Biology at New York University. Named a Fellow of the American Association for the Advancement of Science (AAAS) in 2010 for his research in auditory central nervous system development, his research has been supported by the National Institute on Deafness and Other Communication Disorders and the National Science Foundation. His lab studies synaptic plasticity and central auditory processing, and the phenomenon of hearing loss during development.

Dr. Reh is Professor of Biological Structure and Director of the Neurobiology and Behavior Program at the University of Washington. He is currently a member of the Scientific Advisory Board of the Foundation Fighting Blindness, and of a start-up biotechnology company, Acucela. He has received several awards for his work, including the AHFMR and Sloan Scholar awards and has published over 100 journal articles, reviews and books. Funded by numerous N.I.H. and private foundation grants, his lab is focused on the development and repair of the retina, with an overall goal of understanding the cellular and molecular biology of regeneration in the eye.

Dr. Harris is co-chair of Cambridge Neuroscience and Director of Studies in Neuroscience. He is also Head of the Department of Physiology, Development, and Neuroscience, and is Professor of Anatomy. Elected a Fellow of the Royal Society of London in 2007, he was Professor of Biology at UCSD prior to accepting a position at Cambridge. His lab is working to elucidate the cellular and molecular events that are used to push or induce cells to transition from proliferating stem cells to differentiated neurons and glia, and how particular regions of the nervous system produce the right number of neurons and the right proportions of different neuron subtypes.

From the Back Cover

Development of the Nervous System presents a broad treatment of the basic principles of neural development as exemplified by key experiments and observations from past and recent times.
The text is organized ontogenically, beginning from the induction of the neural primordium and leading to the emergence of behavior. It covers all the major topics that would form the basis of a comprehensive undergraduate curriculum along the way including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and plasticity.
The new text reflects the complete modernization of the field that has been achieved through the use of model organisms, the intensive application of molecular and genetic approaches, and the introduction of new imaging technologies.
Development of the Nervous System is richly illustrated with color photographs and original drawings. These illustrations, combined with clear, concise writing make this a book that is well suited to students approaching this intriguing field for the first time.

* Broad coverage of concepts and experimental strategies
* Full color schematics and photographs of critical experiments
* Outlines the molecular and genetic bases for most developmental events
* Written at a level that is appropriate for undergraduates and beyond
* Includes designs of critical experiments that are easy to understand
* Includes CD with all figures

Edition details

• Publisher: Academic Press
• Publication date: 2005
• Language: English
• ISBN 10: 0126186219
• ISBN 13: 9780126186215
• Binding: Hardcover
• Edition number: 2
• Number of pages: 392