Automation: Genomic and Functional Analyses (Volume 28) (Methods in Microbiology, Volume 28) - Hardcover

Hardcover

ISBN 10: 0125215274 ISBN 13: 9780125215275

Publisher: Academic Press, 1998

Synopsis

Automation is the major future trend for many areas in microbiology, molecular biology, and biochemistry, among other disciplines. It is an enormously exciting area, where techniques and assays that were once repetitive, tedious, and time consuming can be performed robotically, liberating the time of researchers and hospital laboratory workers for more interesting work. Many techniques have now been automated and often miniaturized, including PCR analysis, DNA/RNA preparation, diagnostic test (e.g., Pap tests), compound screening, and of course, sequencing. Some major advances, notably in Professor Leroy Hood's group, have resulted in the ability to perform thousands of assays simultaneously on a normal microscope slide.

Automation, edited by two of the leading experts in the field, presents the very latest experimental techniques explained in detail. This book has succeeded in bringing together researchers at the forefront of clone library construction, genome analysis, sequencing, computational data evaluation and functional analysis, to provide insight into this "new age" of research based on genomic and chemical screening.

• Describes automated procedures used in microbiology and molecular biology
• Includes developments in robotics and vision systems
• Features automation in library picking, presentation and analysis
• Discusses paralogous duplications in microbial genomes
• Covers deciphering genomes through automated large-scale sequencing
• Describes and stresses the need for functional analyses
• Internationally acclaimed contributors, including Professor Leroy Hood

About this title

About the Author

Jorg D. Hoheisel received his Ph.D. in 1988 from the University of Konstanz, Germany, where he studied DNA structures. He was at the ICRF in London, UK from 1988 to 1993, working on genome analysis. Since 1993, he has been Head at the DKFZ (Deutsches Krebsforschungzentrum) in Heidelberg, Germany.

From the Back Cover

Established for almost 30 years, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalised, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research.

Automation, edited by two of the leading experts in the field, presents the very latest experimental techniques explained in detail. The book is structured for ease of reference, and is essential reading for all researchers working in genomics, biochemistry, molecular and cell biology, genetics, microbiology and robotics as well as those in the pharmaceutical/biotechnology industry.

Automation is the major future trend in all biomedical research areas requiring high-throughput analyses. Techniques and assays that were once repetitive, tedious and time consuming can now be performed robotically, liberating the time of laboratory researchers for more interesting work. A multi-author book, this volume has succeeded in bringing together researchers at the forefront of clone library construction, genome analysis, sequencing, computational data evaluation and functional analyses to provide insight into this "new age" of research based on genomic and chemical screening.

Key Features and Contents:

• Describes automated procedures used in microbiology and molecular biology
• Includes developments in robotics and vision systems
• Features automation in library picking, presentation and analysis
• Discusses paralogous duplications in microbial genomes
• Covers deciphering genomes through automated large-scale sequencing
• Describes and stresses the need for functional analyses
• Internationally acclaimed contributors, including Professor Leroy Hood

Edition details

• Publisher: Academic Press
• Publication date: 1998
• Language: English
• ISBN 10: 0125215274
• ISBN 13: 9780125215275
• Binding: Hardcover
• Number of pages: 270
• Editor: Craig Alister G., Hoheisel Jörg D.