Cilia, Part A (Volume 524) (Methods in Enzymology, Volume 524) - Hardcover

Hardcover

ISBN 10: 0123979455 ISBN 13: 9780123979452

Publisher: Academic Press, 2013

Synopsis

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium.

• Continues the legacy of this premier serial with quality chapters authored by leaders in the field
• Covers cilia
• Contains chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium

About this title

About the Author

Wallace Marshall is an electrical engineer by training, who became interested in biology out of a desire to understand how cells solve engineering problems, such as determining the size of organelles. He received his Ph.D. at UCSF with John Sedat, where he studied the diffusional of motion of interphase chromatin using live cell imaging and computational image analysis. He then trained as a postdoc with Joel Rosenbaum at Yale, where he began studying the mechanisms regulating the length of cilia and flagella. He is now Profess of Biochemistry at UCSF, where he lab continues to study the assembly and length regulation of cilia and flagella, as well as the mechanisms that regulate the size of other organelles. His work takes advantage of an integrated combination of methods including genetics, microscopy, and computational modeling, as well as a wide variety of model organisms including Chlamydomonas reinhardtii, Stentor coeruleus, yeast, flatworms, and mammalian cells.

Edition details

• Publisher: Academic Press
• Publication date: 2013
• Language: English
• ISBN 10: 0123979455
• ISBN 13: 9780123979452
• Binding: Hardcover
• Edition number: 1
• Number of pages: 472
• Editor: Marshall Wallace F.