The SV40 Replicon Model for Analysis of Anticancer Drugs - Softcover

Snapka, Robert M.

Softcover

ISBN 10: 0123912199 ISBN 13: 9780123912190

Publisher: Academic Press, 2012

Synopsis

This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments.

About this title

About the Author

Dr. Snapka is an associate professor of Radiology at The Ohio State University, teaching courses in Radiation Biology, DNA Tumor Viruses, Drug Resistance, and Genetic Instability. Dr. Snapka earned his B.S. in Biology and M.S. in Chemistry at North Texas State University. He earned his Ph.D. at the University of California, Irvine and worked as a Research Fellow at the University of California, Berkeley and Massachusetts Institute of Technology. He is the author of over 35 article in refereed journals and is currently conducting research in anticancer drug resistance and drug discovery.

Edition details

• Publisher: Academic Press
• Publication date: 2012
• Language: English
• ISBN 10: 0123912199
• ISBN 13: 9780123912190
• Binding: Paperback
• Number of pages: 208