Anticancer Drug Development - Softcover

9780123911278: Anticancer Drug Development

Softcover

ISBN 10: 0123911273 ISBN 13: 9780123911278

Publisher: Academic Press, 2012

Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided.

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Review

"..this is a really extensive and comprehensive book on the drug development process. ...There is very little overlap between chapters and all are written by experts in the field. Hundreds of useful references are included for those wanting to go further. ...Very good value...and essential reading for both the scientist and Ph.D. student. Definately one for the library to stock." --Paul Loadman, University of Bradford, UK for BRITISH JOURNAL OF CANCER, 2002

"Well-referenced and indexed...this text would be a useful addition to the clinic, research laboratory and institution library." --P. Parsons, Queensland Institute of Medical Research for CANCER FORUM, 2002

From the Back Cover

One of the essential goals in medicine today is to devise therapies leading to the cure or effective control of cancer. The development of new anticancer drugs is central to this goal and in both concept and technology is one of the most rapidly changing areas of science. This multidisciplinary process includes the identification of new therapeutic targets, drug design and synthesis, preclinical testing, and clinical trials. Most scientists and clinicians concerned with anticancer drugs are familiar with only parts of this process. This book provides the best of science and clinical application in a single reference work.

KEY FEATURES:
* One work that can be consulted for all aspects of anticancer drug development
* Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts
* A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death
* Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products
* Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques
* Hundreds of references that allow the reader to access relevant scientific and medical literature
* Clear illustrations, some in color, that provide both understanding of the field and material for teaching
|One of the essential goals in medicine today is to devise therapies leading to the cure or effective control of cancer. The development of new anticancer drugs is central to this goal and in both concept and technology is one of the most rapidly changing areas of science. This multidisciplinary process includes the identification of new therapeutic targets, drug design and synthesis, preclinical testing, and clinical trials. Most scientists and clinicians concerned with anticancer drugs are familiar with only parts of this process. This book provides the best of science and clinical application in a single reference work.

KEY FEATURES:
* One work that can be consulted for all aspects of anticancer drug development
* Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts
* A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death
* Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products
* Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques
* Hundreds of references that allow the reader to access relevant scientific and medical literature
* Clear illustrations, some in color, that provide both understanding of the field and material for teaching