Protein Physics: A Course of Lectures - Softcover

Finkelstein, Alexei V.

9780123908797: Protein Physics: A Course of Lectures

Softcover

ISBN 10: 0123908795 ISBN 13: 9780123908797

Publisher: Academic Press, 2012

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Protein Physics is a lively presentation of the most general problems of protein structure, folding and function from the physics and chemistry perspective, based on lectures given by the authors. It deals with fibrous, membrane and, most of all, with the best studied water-soluble globular proteins, in both their native and denatured states. The major aspects of protein physics are covered systematically, physico-chemical properties of polypeptide chains; their secondary structures; tertiary structures of proteins and their classification; conformational transitions in protein molecules and their folding; intermediates of protein folding; folding nuclei; physical backgrounds of coding the protein structures by their amino acid sequences and protein functions in relation to the protein structure. The book will be of interest to undergraduate and graduate level students and researchers of biophysics, biochemistry, biology and material science.

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Review

"It is not always easy to translate a good lecture course into an equally engaging textbook, but Finkelstein and Ptitsyn have succeeded in this difficult task. The twenty-five chapters are not only an accurate and detailed introduction to the physics of proteins, but also remarkably lively. ...the book is a pleasure to read and is well suited both as a textbook used in a course on protein science and as a tool for self-study." --Ulrich H. E. Hansmann for the BULLETIN OF MATHEMATICAL BIOLOGY, Sept. 2003

"The lectures are unique... anticipating questions from the students, and answering them, with an interspersion of simple examples...a good introduction to protein physics for students, ...will help chemists, physicists, and biologists acquire a widespread knowledge of current issues in protein structure, properties, and reactions." --Harold A. Scheraga, Todd Professor of Chemistry, Cornell University, USA

"Protein Physics provides all the essential information. ...concise, reliable and very well written" --Israel M. Gelfand, Distinguished Professor Rutgers University, USA

"Rigorous and thorough analysis of physical basis of protein structure...unique in its profound professionalism ... free, colloquial style." --Alexander S. Spirin, Professor of Biochemistry, Moscow University, Russia

From the Back Cover

Protein science is at the forefront of the biotechnology revolution. Vast amounts of experimental data on protein structure, folding and action have been accumulated during the past decades and at an accelerated rate in the post-genome era. There is a large and growing number of
students and young researchers entering the field and we need to ensure that their research
is not impeded by their lack of understanding of the basic physics and physical chemistry
behind protein structure and function, in particular behind protein engineering and design.

Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function and introduces the concepts and theories. It deals with fibrous, membrane and water-soluble globular proteins, in both their native and denatured states. The book summarizes and presents in a systematic way the results of several decades of worldwide fundamental research on protein physics, structure and folding.

Protein Physics is aimed at a broad audience of undergraduate and graduate students, as well as being a reference for researchers in academia and industry.

For those with a physics, chemistry or materials science background, the book provides details of protein structure, folding, action and design.
For the biophysicists, biochemists, biologists and medical students it is an invaluable resource on the principles of protein physics and spontaneous self-organization. To ensure a complete understanding of the course by those with a biological background, the book includes simple short-cut material on thermodynamics, statistical physics, and quantum mechanics.

This course is based on lectures now read by Professor A.V.Finkelstein at Moscow State
University. Many of the lectures from this course have been read at international schools and
conferences on protein physics. The book will appeal to those on a wide-range of courses,
including advanced courses on biophysics, biochemistry and soft matter physics and undergraduate courses on chemical physics, chemistry, chemical biology and physics.

"The lectures are unique... anticipating questions from the students, and answering them, with an interspersion of simple examples...a good introduction to protein physics for students, ...will help chemists, physicists, and biologists acquire a widespread knowledge of current issues in protein structure, properties, and reactions."
Harold A. Scheraga, Todd Professor of Chemistry, Cornell University, USA

"Protein Physics provides all the essential information. ...concise, reliable and very well written"
Israel M. Gelfand, Distinguished Professor Rutgers University, USA.

"Rigorous and thorough analysis of physical basis of protein structure...unique in its profound professionalism ... free, colloquial style."
Alexander S. Spirin, Professor of Biochemistry, Moscow University, Russia|Protein science is at the forefront of the biotechnology revolution. Vast amounts of experimental data on protein structure, folding and action have been accumulated during the past decades and at an accelerated rate in the post-genome era. There is a large and growing number of
students and young researchers entering the field and we need to ensure that their research
is not impeded by their lack of understanding of the basic physics and physical chemistry
behind protein structure and function, in particular behind protein engineering and design.

Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function and introduces the concepts and theories. It deals with fibrous, membrane and water-soluble globular proteins, in both their native and denatured states. The book summarizes and presents in a systematic way the results of several decades of worldwide fundamental research on protein physics, structure and folding.

Protein Physics is aimed at a broad audience of undergraduate and graduate students, as well as being a reference for researchers in academia and industry.

For those with a physics, chemistry or materials science background, the book provides details of protein structure, folding, action and design.
For the biophysicists, biochemists, biologists and medical students it is an invaluable resource on the principles of protein physics and spontaneous self-organization. To ensure a complete understanding of the course by those with a biological background, the book includes simple short-cut material on thermodynamics, statistical physics, and quantum mechanics.

This course is based on lectures now read by Professor A.V.Finkelstein at Moscow State
University. Many of the lectures from this course have been read at international schools and
conferences on protein physics. The book will appeal to those on a wide-range of courses,
including advanced courses on biophysics, biochemistry and soft matter physics and undergraduate courses on chemical physics, chemistry, chemical biology and physics.

"The lectures are unique... anticipating questions from the students, and answering them, with an interspersion of simple examples...a good introduction to protein physics for students, ...will help chemists, physicists, and biologists acquire a widespread knowledge of current issues in protein structure, properties, and reactions."
Harold A. Scheraga, Todd Professor of Chemistry, Cornell University, USA

"Protein Physics provides all the essential information. ...concise, reliable and very well written"
Israel M. Gelfand, Distinguished Professor Rutgers University, USA.

"Rigorous and thorough analysis of physical basis of protein structure...unique in its profound professionalism ... free, colloquial style."
Alexander S. Spirin, Professor of Biochemistry, Moscow University, Russia