Fragment Based Drug Design, Volume 493: Tools, Practical Approaches, and Examples (Methods in Enzymology)

0 avg rating
( 0 ratings by Goodreads )
 
9780123812742: Fragment Based Drug Design, Volume 493: Tools, Practical Approaches, and Examples (Methods in Enzymology)

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits.

  • Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens
  • The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD

"synopsis" may belong to another edition of this title.

Top Search Results from the AbeBooks Marketplace

1.

Jon Kolko
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Quantity Available: 1
Seller
firstbookstore
(New Delhi, India)
Rating
[?]

Book Description Book Condition: Brand New. Brand New Original US Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!. Bookseller Inventory # AIND-70549

More Information About This Seller | Ask Bookseller a Question

Buy New
92.33
Convert Currency

Add to Basket

Shipping: FREE
From India to United Kingdom
Destination, Rates & Speeds

2.

Jon Kolko
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Quantity Available: 1
Seller
Bookshub
(Karol Bagh, India)
Rating
[?]

Book Description Book Condition: New. New. US edition. Perfect condition. Customer satisfaction our priority. Bookseller Inventory # ABE-FEB-16887

More Information About This Seller | Ask Bookseller a Question

Buy New
93.39
Convert Currency

Add to Basket

Shipping: FREE
From India to United Kingdom
Destination, Rates & Speeds

3.

Jon Kolko
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Quantity Available: 1
Seller
EBOOKSTORE2010
(New Delhi, ND, India)
Rating
[?]

Book Description Book Condition: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Bookseller Inventory # SHUB16887

More Information About This Seller | Ask Bookseller a Question

Buy New
93.42
Convert Currency

Add to Basket

Shipping: FREE
From India to United Kingdom
Destination, Rates & Speeds

4.

Published by Elsevier Science Publishing Co Inc, United States (2011)
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Hardcover Quantity Available: 10
Seller
Book Depository hard to find
(London, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc, United States, 2011. Hardback. Book Condition: New. New.. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. Bookseller Inventory # EOD9780123812742

More Information About This Seller | Ask Bookseller a Question

Buy New
95.70
Convert Currency

Add to Basket

Shipping: FREE
Within United Kingdom
Destination, Rates & Speeds

5.

Jon Kolko
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Quantity Available: 1
Seller
Romtrade Corp.
(STERLING HEIGHTS, MI, U.S.A.)
Rating
[?]

Book Description Book Condition: New. Brand New Original US Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery. Bookseller Inventory # AUSBNEW-70549

More Information About This Seller | Ask Bookseller a Question

Buy New
96.89
Convert Currency

Add to Basket

Shipping: FREE
From U.S.A. to United Kingdom
Destination, Rates & Speeds

6.

Jon Kolko
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Quantity Available: 1
Seller
Basi6 International
(Irving, TX, U.S.A.)
Rating
[?]

Book Description Book Condition: Brand New. New, US edition. Excellent Customer Service. Bookseller Inventory # ABEUSA-16887

More Information About This Seller | Ask Bookseller a Question

Buy New
96.90
Convert Currency

Add to Basket

Shipping: FREE
From U.S.A. to United Kingdom
Destination, Rates & Speeds

7.

Jon Kolko
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Quantity Available: 2
Seller
BooksForStudent
(West Bloomfield, MI, U.S.A.)
Rating
[?]

Book Description Book Condition: New. Brand New Book In Mint condition. Shipping with Trackable Method. No APO/FPO Addresses Please. Bookseller Inventory # 9780123812742NHS

More Information About This Seller | Ask Bookseller a Question

Buy New
92.32
Convert Currency

Add to Basket

Shipping: 46.14
From U.S.A. to United Kingdom
Destination, Rates & Speeds

8.

KUO, LAWRENCE
Published by Academic Press (2011)
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Hardcover Quantity Available: 10
Seller
Herb Tandree Philosophy Books
(Stroud, GLOS, United Kingdom)
Rating
[?]

Book Description Academic Press, 2011. Hardback. Book Condition: NEW. 9780123812742 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE0892719

More Information About This Seller | Ask Bookseller a Question

Buy New
143
Convert Currency

Add to Basket

Shipping: 3.75
Within United Kingdom
Destination, Rates & Speeds

9.

KUO, LAWRENCE
Published by Academic Press (2011)
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Hardcover Quantity Available: 10
Seller
Herb Tandree Philosophy Books
(Stroud, GLOS, United Kingdom)
Rating
[?]

Book Description Academic Press, 2011. Hardback. Book Condition: NEW. 9780123812742 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE01196810

More Information About This Seller | Ask Bookseller a Question

Buy New
143
Convert Currency

Add to Basket

Shipping: 3.75
Within United Kingdom
Destination, Rates & Speeds

10.

Published by Academic Press
ISBN 10: 0123812747 ISBN 13: 9780123812742
New Hardcover Quantity Available: 1
Seller
IBestBargains, LLC
(Houston, TX, U.S.A.)
Rating
[?]

Book Description Academic Press. Hardcover. Book Condition: New. 0123812747 Brand New Book in Perfect Condition.Fast Shipping with tracking number. Bookseller Inventory # YGDA-SRIADHYA-2788

More Information About This Seller | Ask Bookseller a Question

Buy New
137.90
Convert Currency

Add to Basket

Shipping: 10.77
From U.S.A. to United Kingdom
Destination, Rates & Speeds

There are more copies of this book

View all search results for this book