Biothermodynamics, Part B: 466 (Methods in Enzymology): Volume 466 - Hardcover

Book 104 of 272: ISSN

Johnson, Michael

 
9780123747761: Biothermodynamics, Part B: 466 (Methods in Enzymology): Volume 466
Hardcover
ISBN 10: 0123747767 ISBN 13: 9780123747761
Publisher: Academic Press, 2009

Synopsis

The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.

  • Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules
  • Provides a "must-have" methods volume that keeps MIE buyers and online subscribers up-to-date with the latest research
  • Offers step-by-step lab instructions, including necessary equipment, from a global research community

"synopsis" may belong to another edition of this title.

From the Back Cover

The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.

"About this title" may belong to another edition of this title.

Publisher
Academic Press
Publication date
2009
Language
English
ISBN 10 
0123747767
ISBN 13 
9780123747761
Binding
Hardcover
Number of pages
350