Angiogenesis: Pt. A: In Vivo Systems: In Vivo Systems Pt. A (Methods in Enzymology): Volume 444 - Hardcover

Hardcover

ISBN 10: 0123743133 ISBN 13: 9780123743138

Publisher: Academic Press, 2008

Synopsis

Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. Understanding how angiogenesis "works" and how to control it, will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis cuts across virtually every discipline. The Angiogenesis Foundation identified angiogenesis as a "common denominator" in our most serious diseases. Excessive angiogenesis occurs in diseases such as cancer, diabetic blindness, age-related macular degeneration, rheumatoid arthritis, psoriasis, and many other conditions. Insufficient angiogenesis occurs in diseases such as coronary artery disease, stroke, and delayed wound healing.

• Tried-and-tested techniques written by researchers that developed them, used them, and brought them to fruition
• Provides the "builder's manual" for essential techniques. This is a one-stop shop that eliminates needless searching among untested techniques
• Includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics

About this title

Review

Angiogenesis has been identified as a “common denominator” in society’s most serious diseases and more than $4 billion has been invested in the research and development of angiogenesis-based medicines, making it one of the most heavily funded areas of medical research in history.

Edition details

• Publisher: Academic Press
• Publication date: 2008
• Language: English
• ISBN 10: 0123743133
• ISBN 13: 9780123743138
• Binding: Hardcover
• Number of pages: 400
• Editor: Cheresh David A.