Clinical and Translational Science: Principles of Human Research

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9780123736390: Clinical and Translational Science: Principles of Human Research

Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. This book is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science. * Clinical research is one of the fastest growing fields in private practice and academic medicine with practical biological, physiological, cellular, and therapeutic applications * Contributions from international leaders provide insight into background and future understanding for clinical and translational science * Provides the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context of human research, and the future of human research

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This is the definitive text introducing the new discipline of clinical and translational science. It covers all aspects of this new field, and captures the excitement of novel approaches to investigation of human health and disease, emphasizing drug discovery, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This book begins with experimental design and investigative tools. It moves on to human genetics and pharmacology with a focus on genomic science, clinical trials, epidemiology, outcomes, research, drug discovery and development, and clinical trials. It addresses legal, social and ethical issues of clinical research. * Discusses practical biological, physiological, cellular, and therapeutic applications for one of the fastest growing fields in private practice and academic medicine * Includes contributions from international leaders providing insight into background and future understanding for clinical and translational science * Presents the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context of human research, and the future of human research

Review:

Clinical and Translational Science - Principles of Human Research by Robertson and Williams is as much an important textbook as a guide for translational research in the current era. The book covers a whole breadth of topics written by well known authorities which are of practical relevance to the day-to-day conduct of translational research. Given that more and more translational research is being conducted in more and more developing countries, this book would also find relevance for efforts in developing countries. I am sure many will find this a welcome addition to the current array of books on research methodology, clinical trials and clinical epidemiology. This superbly written textbook full of relevant information and refreshing thoughts and ideas (will) be appreciated by students and teachers of medicine, clinical researchers and policy makers. Khalid Yusoff Professor of Medicine and Dean Faculty of Medicine Universiti Teknology MARA Shah Alam, Malaysia

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Book Description Elsevier Science Publishing Co Inc, United States, 2009. Hardback. Book Condition: New. 274 x 224 mm. Language: English . Brand New Book. Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. This book is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science. Bookseller Inventory # AAZ9780123736390

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Book Description Elsevier Science Publishing Co Inc, United States, 2009. Hardback. Book Condition: New. 274 x 224 mm. Language: English . Brand New Book. Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. This book is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science. Bookseller Inventory # AAZ9780123736390

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Book Description Elsevier Science Publishing Co Inc, 2008. Book Condition: New. 2008. 1st Edition. Hardcover. Introduces the discipline of clinical and translational science. This title covers various aspects of this field, and captures the novel approaches to investigation of human health and disease, emphasizing drug discovery, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. Editor(s): Robertson, David; Williams, Gordon H. Num Pages: 600 pages, black & white illustrations, black & white tables, figures. BIC Classification: MBP. Category: (P) Professional & Vocational. Dimension: 278 x 224 x 39. Weight in Grams: 2044. . . . . . . Bookseller Inventory # V9780123736390

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Book Description Elsevier Science Publishing Co Inc. Book Condition: New. 2008. 1st Edition. Hardcover. Introduces the discipline of clinical and translational science. This title covers various aspects of this field, and captures the novel approaches to investigation of human health and disease, emphasizing drug discovery, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. Editor(s): Robertson, David; Williams, Gordon H. Num Pages: 600 pages, black & white illustrations, black & white tables, figures. BIC Classification: MBP. Category: (P) Professional & Vocational. Dimension: 278 x 224 x 39. Weight in Grams: 2044. . . . . . Books ship from the US and Ireland. Bookseller Inventory # V9780123736390

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