Genetic Algorithms in Molecular Modeling (Principles of QSAR and Drug Design) - Hardcover

Devillers, James

Hardcover

ISBN 10: 0122138104 ISBN 13: 9780122138102

Publisher: Academic Press, 1996

Synopsis

Genetic Algorithms in Molecular Modeling is the first book available on the use of genetic algorithms in molecular design. This volume marks the beginning of an ew series of books, Principles in Qsar and Drug Design, which will be an indispensible reference for students and professionals involved in medicinal chemistry, pharmacology, (eco)toxicology, and agrochemistry. Each comprehensive chapter is written by a distinguished researcher in the field.

Through its up to the minute content, extensive bibliography, and essential information on software availability, this book leads the reader from the theoretical aspects to the practical applications. It enables the uninitiated reader to apply genetic algorithms for modeling the biological activities and properties of chemicals, and provides the trained scientist with the most up to date information on the topic.

• Extremely topical and timely
• Sets the foundations for the development of computer-aided tools for solving numerous problems in QSAR and drug design
• Written to be accessible without prior direct experience in genetic algorithms

About this title

About the Author

James Devillers is currently a Professor in Ecology, Zoology, Ecotoxicology, and Phytopathology at an Agricultural School of Graduate Engineers (ISARA) in Lyon, France,since 1983. Devillers is also a Professor in Environmental Chemistry at a Chemical School of Graduate Engineers (ICPI), and a Senior Lecturer in QSAR and Ecotoxicology for the Centre of Environmental Sciences (Metz), Private Institutes, and the EEC. He is also the President of the Centre de Traitement de l'Information Scientifique, which is a private company specializing in QSAR studies, drug design, statistical analysis, and data validation. Devillers has published many articles, six books, and is a member of various societies and institutions including: The International QSAR Society, the European Group for the QSAR Studies, the International Neural Network Society, the Institute of Electrical and Electronics Engineers (IEEE), the American Chemical Society (ACS), the Society of Environmental Toxicology and Chemistry (SETAC), the Societe d'Ecotoxicologie Fondamentale et Appliquee (SEFA), and the Societe Linneenne de Lyon (SLL). He is Editor-in-Chief of two journals: SAR and QSAR in Environmental Research (Gordon and Breach Science Publishers), and Toxicology Modeling (Carfax Publishing Company); as well as a series of books called Handbooks of Ecotoxicological Data (Gordon and Breach Science Publishers). Devillers is also a member of the editorial board of three journals, these are: Ecological Modelling (Elsevier), Xenobiotica (Taylor & Francis), and Journal of Biological Systems (World Scientific).

From the Back Cover

A multi-authored and comprehensive text, Genetic Algorithms in Molecular Modeling, enables professionals in QSAR and drug design to gain a thorough understanding of genetic algorithms (GAs) which are powerful search methods based on the mechanics of natural selection and genetics. The chapters are written in a clear, concise, and didactic style, and present different examples of real-life GA applications in medicinal chemistry, pharmacology, and applied chemistry.

Edition details

• Publisher: Academic Press
• Publication date: 1996
• ISBN 10: 0122138104
• ISBN 13: 9780122138102
• Binding: Hardcover
• Language: English
• Number of pages: 327