Foundations of Comparative Genomics - Hardcover

Mushegian, Arcady R.

 
9780120887941: Foundations of Comparative Genomics
Hardcover
ISBN 10: 0120887940 ISBN 13: 9780120887941
Publisher: Academic Press, 2007

Synopsis

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics.

  • Presents an historic overview of genome biology and its achievements
  • Includes topics not covered in other books such as minimal and ancestral genomes
  • Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level
  • Critically reviews horizontal gene transfer and other contentious issues
  • Covers comparative virology as a somewhat overlooked foundation of modern genome science

"synopsis" may belong to another edition of this title.

About the Author

Arcady R. Mushegian is Director of Bioinformatics at Stowers Institute for Medical Research in Kansas City and Professor of Microbiology at Kansas University Medical Center. He was born in Moscow, USSR, and graduated from Moscow State University.

From the Back Cover

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics.

"About this title" may belong to another edition of this title.

Publisher
Academic Press
Publication date
2007
Language
English
ISBN 10 
0120887940
ISBN 13 
9780120887941
Binding
Hardcover
Edition number
1
Number of pages
280

Other Popular Editions of the Same Title

9780124054400: Foundations of Comparative Genomics

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ISBN 10:  0124054404 ISBN 13:  9780124054400
Publisher: Academic Press, 2014
Softcover