Advances in Genetics (39): v. 39 - Hardcover

Hardcover

ISBN 10: 0120176394 ISBN 13: 9780120176397

Publisher: Academic Press Inc, 1999

Synopsis

Advances in Genetics increases its focus on modern human genetics and its relation to medicine with the merger of this long-standing serial with Molecular Genetic Medicine. This merger affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Volume 39 of Advances in Genetics completes the trilogy of volumes authored by Dr. Igor Zhimulev of the Institute of Cytology and Genetics in Novosibirsk, Russia. This set comprises what is perhaps the most comprehensive collection of volumes dedicated to the study of polytene chromosomes. Volume 39 picks up where the previous two volumes, 34 and 37, left off. It covers the organization of genetic material in the morphological structures of the interphase chromosome, the chromomeres and the interchromomeric regions, and the structural changes occurring during the activation of the chomomeres, the puffs.

About this title

Review

"@from:Praise for the Series Outstanding both in variety and in the quality of its contributions. --NATURE Can be highly recommended to geneticists, and biologists in general...will prove to be of high importance for the development of the science of genetics. --SCIENCE The high standards of the Advances series of Academic Press are now almost taken for granted. The new volume matches up to the revolutionary and all-embracing developments in genetics that have occurred over the last few years. --SCIENCE PROGRESS This text would be of interest to geneticists, botanists, developmental biologists, molecular biologists, and other interested individuals. --BIOLOGICAL ABSTRACTS

From the Back Cover

Advances in Genetics increases its focus on modern human genetics and its relation to medicine with Volume 33 of this long-standing serial. The recent merger of Molecular Genetic Medicine with Advances in Genetics affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
In this volume, Petes and Pukkila synthesize the latest research on meiotic recombination, with specific reference to crossover and gene conversions. The "absurd size and complex" structure of the Dystrophin gene is considered in another chapter, with discussions of strategies for future diagnosis and treatment of muscular dystrophy. Two chapters also examine the molecular genetics of sex determination, including the influence of maternal age and resulting chromosomal aberrations. Volume 33 also includes a review of the PAX and HOX gene families and their links to the developmental process, cellular growth control, and forms of cancer. Case studies of thrombophilia, Menkes, and Wilson diseases are used to exemplify the genetic disorders of blood clotting, copper deficiency, and toxicity, respectively. Triman takes a genetic approach to understanding the function of ribosomal RNA using E. coli as the model best able to reveal the inherent complications of the translation process. Leach and O'Connell describe the use of radiation hybrids for constructing high-resolution maps of the human genome. With these reviews the alliance of Molecular Genetic Medicine with Advances in Genetics is completed under the banner of Advances in Genetics.
The merged serial
* Presents technical and historical overviews of molecular biology applied to disease detection, diagnosis, and treatment
* Chronicles the continuing explosion of knowledge in molecular genetic medicine by highlighting current approaches to understanding human illness
* Documents the revolution in human and molecular genetics leading to a new field of medicine|Advances in Genetics increases its focus on modern human genetics and its relation to medicine with Volume 33 of this long-standing serial. The recent merger ofMolecular Genetic Medicine with Advances in Genetics affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
In this volume, Petes and Pukkila synthesize the latest research on meiotic recombination, with specific reference to crossover and gene conversions. The "absurd size and complex" structure of theDystrophin gene is considered in another chapter, with discussions of strategies for future diagnosis and treatment of muscular dystrophy. Two chapters also examine the molecular genetics of sex determination, including the influence of maternal age and resulting chromosomal aberrations. Volume 33 also includes a review of the PAX and HOX gene families and their links to the developmental process, cellular growth control, and forms of cancer. Case studies of thrombophilia, Menkes, and Wilson diseases are used to exemplify the genetic disorders of blood clotting, copper deficiency, and toxicity, respectively. Triman takes a genetic approach to understanding the function of ribosomal RNA using E. coli as the model best able to reveal the inherent complications of the translation process. Leach and O'Connell describe the use of radiation hybrids for constructing high-resolution maps of the human genome. With these reviews the alliance ofMolecular Genetic Medicine with Advances in Genetics is completed under the banner ofAdvances in Genetics.
The merged serial
* Presents technical and historical overviews of molecular biology applied to disease detection, diagnosis, and treatment
* Chronicles the continuing explosion of knowledge in molecular genetic medicine by highlighting current approaches to understanding human illness
* Documents the revolution in human and molecular genetics leading to a new field of medicine

Edition details

• Publisher: Academic Press Inc
• Publication date: 1999
• Language: English
• ISBN 10: 0120176394
• ISBN 13: 9780120176397
• Binding: Hardcover
• Number of pages: 500
• Editor: Hall Jeffrey C., Dunlap Jay C., Friedmann Theodore, Giannelli Francesco