Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

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9780071714457: Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY

Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation.

A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications.

Coverage includes:

  • Signals and systems
  • Model requirements
  • Conceptual models
  • Mathematical models
  • Software implementation
  • Simulation results and model validation
  • Cardiorespiratory system model
  • Circulation
  • Respiration
  • Physiologic control
  • Sensitivity analysis of a cardiovascular model
  • Design of model-driven acute care training simulators

“Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). …His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. …The ample illustrations and tables also break up the text and make reading the book easier on the eyes. …concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014

“This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. …The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. …I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012
Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.

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About the Author:

Willem van Meurs, Ph.D., is the co-inventor of the Human Patient Simulator. He is a consultant at Medical Education Technologies, Inc., and conducts modeling and simulation teaching and research at the University of Porto, Portugal. Dr. van Meurs was the president of the Society in Europe for Simulation Applied to Medicine from 2005-2007. He has published more than 20 full papers in peer-reviewed international journals and books and co-authored eight U.S. patents on modeling and simulation techniques.

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Book Description McGraw-Hill Education - Europe, United States, 2011. Hardback. Book Condition: New. 231 x 150 mm. Language: English . Brand New Book. Complete coverage of everything from theory to practical modeling and simulation techniques of human physiology for medical engineers Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespitory Physiology is a single compact and consistent reference. You will acquire an understanding of the theoretical and practical aspects of modeling and simulation of dynamic systems, as well as models of the cardiorespiratory systems and their natural and pharmacologic controls. When working through the text and examples, you will also acquire the skills to evaluate and adapt existing physiologic models or create new ones for specific applications and integrate clinical, physiological, physical, mathematical, and software engineering considerations in a goal-oriented fashion. Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespitory Physiology Presents several applications of modeling and simulation of human cardiorespiratory physiology Includes state variable models of the cardiovascular and respiratory systems so that you can model other physiological systems using state variable techniques Is written by the immediate past president of SESAM (Society in Europe for Simulation Applied to Medicine) Covers both theory and practical aspects of modeling and simulation of dynamic systems Authoritative coverage: Introduction; Interface and Model Requirement; Conceptual Models; Mathematical Models; Discretization and Simulation Results; Interpretation of Simulation Results; The Cardiovascular System; Respiration; Physiologic and Pharmacologic Control; Multiple Models; Physical and Hybrid Models; Modeling Age and Disease; Setting Requirements for Educational; Simulators and Models References. Bookseller Inventory # AA39780071714457

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Book Description McGraw-Hill Education - Europe, United States, 2011. Hardback. Book Condition: New. 231 x 150 mm. Language: English . Brand New Book. Complete coverage of everything from theory to practical modeling and simulation techniques of human physiology for medical engineers Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespitory Physiology is a single compact and consistent reference. You will acquire an understanding of the theoretical and practical aspects of modeling and simulation of dynamic systems, as well as models of the cardiorespiratory systems and their natural and pharmacologic controls. When working through the text and examples, you will also acquire the skills to evaluate and adapt existing physiologic models or create new ones for specific applications and integrate clinical, physiological, physical, mathematical, and software engineering considerations in a goal-oriented fashion. Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespitory Physiology Presents several applications of modeling and simulation of human cardiorespiratory physiology Includes state variable models of the cardiovascular and respiratory systems so that you can model other physiological systems using state variable techniques Is written by the immediate past president of SESAM (Society in Europe for Simulation Applied to Medicine) Covers both theory and practical aspects of modeling and simulation of dynamic systems Authoritative coverage: Introduction; Interface and Model Requirement; Conceptual Models; Mathematical Models; Discretization and Simulation Results; Interpretation of Simulation Results; The Cardiovascular System; Respiration; Physiologic and Pharmacologic Control; Multiple Models; Physical and Hybrid Models; Modeling Age and Disease; Setting Requirements for Educational; Simulators and Models References. Bookseller Inventory # AA39780071714457

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